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Actinic Keratosis clinical trials

View clinical trials related to Actinic Keratosis.

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NCT ID: NCT01541553 Completed - Actinic Keratosis Clinical Trials

A Sequential Treatment Regimen of Cryotherapy and Picato® for the Treatment of Actinic Keratosis on the Face and Scalp

Start date: March 2012
Phase: Phase 3
Study type: Interventional

The purpose of this trial is to compare the rate of complete clearance of actinic keratosis (AK) using sequential cryotherapy and field treatment with PEP005 Gel compared to cryotherapy alone.

NCT ID: NCT01541228 Completed - Actinic Keratosis Clinical Trials

Photodynamic Treatment of Actinic Keratoses With Different Light Doses

Start date: April 2010
Phase: N/A
Study type: Interventional

Aim of the study: To evaluate clinical effectiveness of two different light doses when treating actinic keratoses with photodynamic therapy with 20% 5-aminolevulinic acid.

NCT ID: NCT01525329 Terminated - Actinic Keratosis Clinical Trials

Combination Therapy With 5-Fluorouracil and Photodynamic Therapy in Post-transplant Premalignant Skin Disease

Start date: September 2011
Phase: Phase 3
Study type: Interventional

This randomized, intra-patient comparative study is designed to investigate the combination regimen of 5-fluorouracil cream (5FU) and Photodynamic Therapy (PDT), versus PDT alone, for its ability to generate significantly elevated levels of the target photosensitizer, protoporphyrin IX (PpIX), in lesions of actinic keratoses (AKs) and to more effectively treat and prevent recurrence of AKs. The target population comprises patients with solid organ transplants (renal, hepatic), as well as normal (immunocompetent) subjects to control for possible influences of immunosuppression.

NCT ID: NCT01516515 Completed - Actinic Keratosis Clinical Trials

Efficacy and Safety Phase II Study of SR-T100 to Treat Actinic Keratosis

Start date: February 2013
Phase: Phase 2
Study type: Interventional

This Phase II study is to evaluate the efficacy of SR-T100 gel with 2.3% of SM in Solanum undatum plant extract in patient with Actinic Keratosis (AK).

NCT ID: NCT01493921 Completed - Actinic Keratosis Clinical Trials

Efficacy Study & Safety Evaluation of SR-T100 Gel in Actinic Keratosis Treatment

Start date: October 2011
Phase: Phase 3
Study type: Interventional

Studies of SR-T100 gel and its clinical relevance in the treatment of AK, providing adequate measured outcomes for skin lesion treatment. In addition to the high complete response rate (90.0%) as compared with the conventional therapy, the most significant result was that no undesirable side effects were associated with the use of SR-T100 gel. The result also shows approximately 80% of study subjects had a complete response in phase II clinical trial conducted in Taiwan; hence, result from our study model suggested SR-T100 gel offers beneficial therapeutic values in treatment of AK is harmless to the skin as well as high tolerance level displayed by majority of patients.

NCT ID: NCT01481155 Active, not recruiting - Actinic Keratosis Clinical Trials

Comparative Study of Photodynamic Therapy vs. CO2 Laser Therapy in Treatment of Actinic Keratoses

Start date: March 2011
Phase: N/A
Study type: Interventional

The purpose of this study is to determine whether photodynamic therapy or CO2 laser therapy is superior in the treatment of actinic keratoses with respect to efficacy and side effects.

NCT ID: NCT01475955 Completed - Actinic Keratosis Clinical Trials

Short-incubation Levulan Photodynamic Therapy Versus Vehicle for Face/Scalp Actinic Keratosis (AK)

Start date: December 2011
Phase: Phase 2
Study type: Interventional

The purpose of this study is to determine if Levulan Photodynamic Therapy (PDT) is safe and effective in the treatment of actinic keratosis when applied to broad areas on the face and scalp for 1, 2 and 3 hours.

NCT ID: NCT01459393 Completed - Actinic Keratosis Clinical Trials

Comparison Between 5-aminolevulinic Acid Photodynamic Therapy Versus Cryotherapy for Actinic Keratosis Treatment

Start date: November 2010
Phase: Phase 3
Study type: Interventional

This study aims to compare in a prospective and randomized way actinic keratosis treatment with 5-aminolevulinic acid photodynamic therapy versus cryotherapy, from the standpoint of therapeutic efficacy, pain, and cosmetic results.

NCT ID: NCT01453179 Completed - Actinic Keratosis Clinical Trials

Long-term Effects of Imiquimod and Diclofenac in Actinic Keratoses (LEIDA 2)

LEIDA 2
Start date: October 2011
Phase: Phase 4
Study type: Interventional

This clinical trial serves the purpose to compare the long-term effects of a treatment of actinic keratosis - your skin disorder - using Aldara® 5% cream (Imiquimod) or Solaraze® 3% gel (Diclofenac) on the face or the scalp. In particular, it should be found out whether the healing effect of these two medications on the skin lesions (i.e. the damaged skin parts) can be maintained for a prolonged period.

NCT ID: NCT01449513 Completed - Actinic Keratosis Clinical Trials

PEP005 Gel - Biological Effects in Actinic Keratosis Assessed by Reflectance Confocal Microscopy

Start date: September 2011
Phase: Phase 1
Study type: Interventional

This trial will be conducted to explore the biological effects in the skin following treatment with PEP005 Gel, 0.05% administered for two consecutive days, assessed by reflectance confocal microscopy.