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Clinical Trial Summary

This is a prospective clinical trial in which 30 patients will receive a brief (5-day or 14-day) supplementation with 10,000 IU of Vitamin D, prior to receiving aminolevulinic acid (ALA)- blue light PDT for the treatment of actinic keratoses (AKs).


Clinical Trial Description

This is a phase 2 clinical trial of patients with actinic keratosis (AK) that will examine a combination regimen of Vitamin D plus PDT, and compare its efficacy to controls who underwent PDT alone in a prior study from the Maytin group (IRB 16-1615). Patients will be enrolled at the Cleveland Clinic. Each patient will be matched to patients from the prior study based upon baseline calcidiol levels. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT04482322
Study type Interventional
Source The Cleveland Clinic
Contact Jeffrey Negrey, MA
Phone 216-636-5504
Email negreyj2@ccf.org
Status Recruiting
Phase N/A
Start date January 13, 2020
Completion date December 31, 2022

See also
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