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Actinic Keratoses clinical trials

View clinical trials related to Actinic Keratoses.

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NCT ID: NCT05740969 Recruiting - Actinic Keratoses Clinical Trials

Gene and Protein Expression Profiles After Treatment of Actinic Keratoses

PACKS
Start date: February 1, 2023
Phase: Phase 2
Study type: Interventional

The primary aim of this study is to investigate the effect of 5-fluorouracil, imiquimod, and melatonin for actinic keratosis on immunological gene, and protein expressions profiles. Secondarily, the aim is to assess the effect of the treatment on the histopathology of actinic keratoses.

NCT ID: NCT05725213 Completed - Actinic Keratoses Clinical Trials

ADL-PDT Under Routine Clinical Conditions in Patients With Actinic Keratosis

Start date: November 1, 2022
Phase:
Study type: Observational

The objective of this non-interventional study (NIS) is to gain comprehensive insights into the practicability of ADL-PDT with Metvix® in patients with actinic keratoses under real-world conditions.

NCT ID: NCT05662202 Recruiting - Actinic Keratoses Clinical Trials

Study to Evaluate the Safety, Tolerability and Efficacy of BF-200 ALA (Ameluz®) in the Field-directed Treatment of Actinic Keratosis (AK) on the Extremities and Neck/Trunk With Photodynamic Therapy (PDT) Using a RhodoLED Lamp

Start date: December 12, 2022
Phase: Phase 3
Study type: Interventional

The aim of this study is to test the safety. tolerability and efficacy of field-directed photodynamic therapy (PDT) with 10% aminolevulinic acid gel (Ameluz®, BF-200 ALA) in combination with one of the narrow spectrum red light RhodoLED lamps in comparison to vehicle treatment for actinic keratosis (AK) on the extremities and neck/trunk.

NCT ID: NCT05522036 Completed - Actinic Keratoses Clinical Trials

Clinical Evaluation of a Short Illumination Duration (35 Minutes) When Performing PDT of AK Using the Dermaris ®

Dermaris-35
Start date: January 1, 2022
Phase: N/A
Study type: Interventional

This clinical study aims aims to evaluate the clinical outcomes of SDL-PDT (simulated daylight Photodynamic Therapy) using the Dermaris in patients treated for AK lesions of the scalp at our medical dermatology center using only 35 minutes low-intensity light exposure.

NCT ID: NCT05456334 Active, not recruiting - Actinic Keratoses Clinical Trials

New Treatments for Actinic Keratoses of the Scalp

Start date: March 24, 2016
Phase: N/A
Study type: Interventional

This blinded controlled 2-year study on 120 patients with 2 or more actinic keratoses, compare the efficacy and tolerability of pulsed dye-laser- mediated photodynamic therapy compared to conventional photodynamic therapy and fractional-laser assisted daylight photodynamic therapy compared to daylight photodynamic therapy.

NCT ID: NCT05365386 Completed - Actinic Keratoses Clinical Trials

Efficacy and Safety of Tixel Treatment on Facial and/or Scalp Actinic Keratoses.

Start date: May 17, 2022
Phase: N/A
Study type: Interventional

Evaluation of the Efficacy and Safety of a thermal fractional skin treatment system (Tixel) for the treatment of facial and/or scalp actinic keratoses

NCT ID: NCT05202860 Active, not recruiting - Clinical trials for Squamous Cell Carcinoma

Impact of Human Papillomavirus (HPV) Vaccination on Burden of Disease in Patients With Actinic Keratosis

VAXAK
Start date: May 9, 2022
Phase: Phase 2
Study type: Interventional

A double-blind, randomized, placebo controlled intervention trial on patients with actinic keratosis.

NCT ID: NCT05164393 Active, not recruiting - Actinic Keratoses Clinical Trials

Phase I/IIa Trial to Evaluate AVX001 Gel in Doses of 1% or 3% Compared With Vehicle Over Four Weeks of Field-directed Treatment Period in Adult Subjects With AK

COAKS
Start date: November 2, 2021
Phase: Phase 1/Phase 2
Study type: Interventional

Actinic keratosis (AK), also known as solar keratosis, is a common skin condition characterised by abnormal growth of skin cells caused by long-term sun exposure. AK is considered to be a precancerous lesion, and is therefore commonly treated to reduce the risk of malignant transformation into skin cancer. The trial is a randomised, double-blind, vehicle-controlled, dose-comparison trial in which adult subjects with AK grade 1 or 2 will be treated with AVX001 silicone-based gel in doses of 1% or 3% or with a gel vehicle for a 4-week field-directed treatment period. Subjects will be followed up for 8 weeks after the treatment period. The primary objective is to evaluate the local tolerability of daily applications of AVX001 gel in doses of 1% or 3% and compare with vehicle.

NCT ID: NCT05078827 Completed - Actinic Keratoses Clinical Trials

Therapeutic Equivalence of Fluorouracil Cream, 5% Compared With Fluorouracil 5% Topical Cream of MylanPharmaceuticals Inc., U.S.A in the Treatment of Actinic Keratosis

Start date: March 1, 2022
Phase: Phase 3
Study type: Interventional

Fluorouracil is recommended for the topical treatment of multiple actinic or solar keratoses. In the 5% strength, it is also useful in the treatment of superficial basal cell carcinomas when conventional methods are impractical, such as with multiple lesions or difficult treatment sites.

NCT ID: NCT04969419 Completed - Melanoma (Skin) Clinical Trials

Incidence of Melanoma and Non-melanoma Skin Cancer in People With Vitiligo

Start date: June 18, 2021
Phase:
Study type: Observational

This study examines melanoma and nonmelanoma skin cancer in people diagnosed with vitiligo compared to matched controls.