ACTH Clinical Trial
Official title:
Adrenocorticotropic Hormone Stability on Whole Blood
ACTH is a peptide secreted by pituitary gland and plays an important role in regulating
cortisol secretion. ACTH is determined in plasma by immunoassays using specific antibodies.
Its determination is difficult because of instability in whole blood. Several factors which
influence ACTH stability in blood before analysis have been identified: temperature,
hemolysis, time to centrifugation and presence of protease inhibitors. Published results on
ACTH whole blood stability seem contradictory.
The objective of this study is to evaluate the effect of aprotinin in 10 healthy volunteers.
ACTH measurements will be performed on cobas e602 (Roche Diagnostics, Mannheim, Germany).
n/a
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