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ACS - Acute Coronary Syndrome clinical trials

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NCT ID: NCT05323136 Terminated - Clinical trials for ACS - Acute Coronary Syndrome

Evaluate the Effects of Renal Impairment on the Pharmacokinetics and Pharmacodynamics

Start date: April 15, 2022
Phase: Phase 1
Study type: Interventional

The study is a multicenter, Phase 1, open-label, sequential, adaptive, single dose, PK/PD study in subjects with moderate and severe RI and healthy volunteers (HV).

NCT ID: NCT04062383 Terminated - Clinical trials for ACS - Acute Coronary Syndrome

Positive Emotions After Acute Coronary Events at Northwestern University

PEACE-NU
Start date: February 24, 2020
Phase: N/A
Study type: Interventional

This study is a single-arm, 12-week trial to test the feasibility of a PP-MI intervention for patients recently admitted following ACS. PP-MI is a novel positive psychology-based health behavior intervention that is adapted for patients hospitalized for ACS. The intervention aims to cultivate positive emotions in this vulnerable population that could provide broad and significant health benefits, and may have distinct-and more powerful-effects than simply attempting to dampen negative emotions. The primary aim is to assess whether the intervention exercises are feasible and linked with immediate boosts in positive affect upon completion. The secondary goal is to provide the research team with greater experience recruiting inpatients with an ACS, successfully completing intervention sessions, and administering psychological and medical assessments by phone.