Acne Clinical Trial
Official title:
Efficacy & Safety of Clindamycin Phosphase 1.2% and Tretinoin 0.025% Gel vs. Vehicle for the Treatment of Acne and Acne-Induced Post Inflammatory Hyperpigmentation in Patients With Skin of Color
The purpose of this study is ascertain the efficacy and safety of Clindamycin
Phosphate 1.2% and Tretinoin 0.025% in the treatment of Acne and Post
Inflammatory Hyperpigmentation in patients with skin of color.
Acne is a chronic disorder of the pilosebaceous glands characterized by
inflammatory papules, pustules, opened and closed comedones, cysts and
nodules. Post inflammatory hyperpigmentation is a condition in which an
inflammation from a disease such as acne, trauma, or abrasion results in areas
of the skin with increased melanin content compared to the surrounding skin.
There are several treatments available for acne, which include benzoyl
peroxide,antibiotics (topical or oral), and topical retinoids (tretinoin,
tazarotene, adapalene). Combination therapy, such as topical retinoid and
clindamycin, has been shown to be more effective than monotherapy in
addressing all pathogenic factors of acne.
;
Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Single Group Assignment, Masking: Double Blind (Subject, Investigator), Primary Purpose: Treatment
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Completed |
NCT05097157 -
Study To Assess A Radiofrequency Microneedling Device For Dermatologic Conditions
|
N/A | |
| Completed |
NCT05131373 -
Safety, Tolerability, and Immunogenicity of ORI-A-ce001 for the Treatment of Acne Vulgaris
|
Phase 1 | |
| Completed |
NCT04806594 -
Clinical Investigation on the Safety and Clinical Performance of Papix Acne Scar.
|
N/A | |
| Recruiting |
NCT03465150 -
Creation of a Monocentric Cohort of Patients Treated for Acne at the Nantes University Hospital
|
||
| Completed |
NCT02250859 -
A Pharmacokinetic Study of Minocycline in Male and Female Volunteers
|
Phase 1 | |
| Completed |
NCT01206348 -
Combination Treatment for Moderate to Severe Acne
|
Phase 4 | |
| Terminated |
NCT01193764 -
Study Assessing the Effect of Chocolate Consumption in Subjects With A History of Acne Vulgaris
|
N/A | |
| Completed |
NCT00725439 -
An Open Label Trial to Assess the Safety and Efficacy of Oral R115866 in the Treatment Facial Acne
|
Phase 2 | |
| Completed |
NCT05640388 -
Assessment of a Cosmetic Product Effect on the Host/Microorganism Relationship in Acneic Subjects
|
||
| Completed |
NCT04873089 -
Efficacy Study of Cosmetic Product RV3278AET0943 Versus Non-treated Group in Adults With Oily and Acne Prone Skin
|
||
| Recruiting |
NCT05941065 -
Study of Skin Balancing Gel Cream Safety and Influence of Skin Microbiome on Acne Prone Skin
|
N/A | |
| Recruiting |
NCT06120452 -
A Clinical Trial to Evaluate the Effectiveness of an Acne Serum in Improving Facial Acne and Post-Acne Pigmentation
|
N/A | |
| Completed |
NCT04300010 -
Blue Light Therapy of C. Acnes
|
Phase 4 | |
| Recruiting |
NCT06202274 -
Clinical Study to Evaluate the Safety and Efficacy of Candela Technology
|
N/A | |
| Completed |
NCT04559022 -
Pilot Study Investigating the Efficacy of Fat Grafting as a Treatment for Male and Female Facial Acne Scarring
|
N/A | |
| Terminated |
NCT02431494 -
Safety and Preliminary Efficacy of Combination Therapy for the Treatment of Acne Vulgaris
|
N/A | |
| Completed |
NCT05469880 -
Efficacy and Tolerance of Formula 609613 37 in Acneic Patients
|
N/A | |
| Completed |
NCT02944461 -
Efficacy and Safety of Aczone 7.5% Gel in the Treatment of Truncal Acne Vulgaris
|
Phase 4 | |
| Completed |
NCT01951417 -
Adapalene BPO Gel Pump, Moisturizer SPF 30 and Foam Wash in Patients With Mild to Moderate Acne Vulgaris
|
Phase 4 | |
| Completed |
NCT01701024 -
Clinical Study to Test the Efficacy and Safety of ACYC to Treat Moderate to Severe Acne
|
Phase 3 |