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NCT03933033 Clinical Trial

Erbium-YAG Laser Versus Platelet Rich Plasma in the Treatment of Atrophic Acne Scars

Acne Vulgaris Clinical Trial

Official title:
Fractional Erbium-YAG Laser Versus Platelet Rich Plasma in the Treatment of Atrophic Acne Scars: A Randomized Clinical Trial

Clinical Trial Details — Status: Completed

Administrative data
NCT number NCT03933033
Other study ID # Erbium Yag
Secondary ID
Status Completed
Phase N/A
First received
Last updated
Start date June 1, 2017
Est. completion date February 28, 2019

Study information
Verified date April 2019
Source Aswan University Hospital
Contact n/a
Is FDA regulated No
Health authority
Study type Interventional

Clinical Trial Summary

This study aim to assess the efficacy of Er-YAG laser 2940nm and PRP as a single line of treatment in comparison with combined treatment in atrophic post acne scars.

Recruitment information / eligibility
Status Completed
Enrollment 75
Est. completion date February 28, 2019
Est. primary completion date August 31, 2018
Accepts healthy volunteers No
Gender All
Age group 18 Years to 38 Years
Eligibility Inclusion Criteria:

- patients with atrophic post acne scars classified on the basis of Goodman and Baron's Qualitative classification, no active acne lesions and patients with atrophic scars only

Exclusion Criteria:

- patients with positive history of keloidal tendency, positive history of bleeding tendency, platelet disorder, patients with any acute infection on face like, herpes, folliculitis, patients with HIV, HBsAg, patients with a history of autoimmune diseases or patients on immunosuppressive drugs.

Study Design

Related Conditions & MeSH terms

Intervention

Device:
• Fractional Erbium Yag Laser
Multiple sessions of Fractional Erbium Yag Laser
Procedure:
• Platelet Rich Plasma
Multiple injections of Platelet Rich Plasma

Locations
Country Name City State
Egypt Aswan University Hospital Aswan

Sponsors (2)
Lead Sponsor Collaborator
Aswan University Hospital South Valley University

Country where clinical trial is conducted

Egypt, 

Outcome
Type Measure Description Time frame Safety issue
Primary Change in grade of acne scares according toQualitative scarring grading system of Goodman and Baron Grade of acne scares improvement after treatment 6 months
Primary Change in clinical appearance of acne scare accordinga four-point scale for assessment of clinical improvement of skin smoothness improvement of acne scares as evaluated by sequential photos 6 month
Primary Change in patient satisfaction usinga four-point scale; Grade 4 highly satisfied, Grade 3 satisfied, Grade 2 neutral and Grade 1 dissatisfied increase in patient satisfaction after treatment 6 month
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