Acne Vulgaris Clinical Trial
Official title:
Prevalence of Helicobacter Pylori in Patients With Acne Vulgaris
The objective of the study is to investigate prevalence of H.Pylori infection among acne vulgaris patients.
The study included patients with acne vulgaris and healthy control participants. The study
recruited both sexes, all grades of acne, adolescents and young adults.
All patients were subjected to complete history, general and skin examination Acne vlugaris
Patients were classified into mild, moderate and severe according to the classification of
American Academy of dermatology for acne vulgaris.
Detection of H. pylori infection:
Blood and stool samples were taken from each participant and was directly transferred to
laboratory for detection of H. Pylori antigen and antibody.
An enzyme-linked immune sorbent assay (ELISA) was used for quantitative assessment of IgG
antibodies against H.Pylori in human serum.
A monoclonal antibodies based enzyme-linked immunosorbent assay was used to detect H.Pylori
specific antigen in stool samples.
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