De Novo Lipogenesis of Sebaceous Glands in Acne

Status Completed

Clinical Trial Summary

There are two purposes of this study: 1. First, the investigators want to see what the differences are in de novo sebaceous lipid production of people with and without acne. 2. Secondly, the investigators want to know what happens to sebaceous gland de novo lipid production before and after treatment with topical tretinoin and oral isotretinoin.

Clinical Trial Description

The primary objective of this study is to understand how de novo lipid production of sebaceous glands are altered in acne and with acne directed therapy. Hypothesis 1: The overall de novo lipogenesis will be increased in those with acne Hypothesis 2: Treatment with topical tretinoin and systemic isotretinoin will reduce de novo lipogenesis. ;

Study Design

Related Conditions & MeSH terms

Acne Vulgaris

Clinical Trial Details

NCT number	NCT02620813
Study type	Interventional
Source	University of California, Davis
Contact
Status	Completed
Phase	Early Phase 1
Start date	October 2015
Completion date	October 12, 2017

View Details

See also
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