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Acne Vulgaris clinical trials

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NCT ID: NCT00377000 Completed - Acne Vulgaris Clinical Trials

A Pilot, Multi-Center, Patient Preference Study Comparing Two Clindamycin/Benzoyl Peroxide Gels.

Start date: November 2005
Phase: Phase 4
Study type: Interventional

Evaluate patient preference factors comparing two clindamycin/benzoyl peroxide gels. One dispensed in a pump presentation, the other in a tube presentation.

NCT ID: NCT00361322 Completed - Acne Vulgaris Clinical Trials

Efficacy and Safety of a Preparation Containing an Antibiotic and Anti-Inflammatory Agent in Acne Vulgaris

Start date: April 2005
Phase: Phase 1/Phase 2
Study type: Interventional

The concept behind our study was to combine an effect of antibiotic and anti-inflammatory agents for a more efficient acne therapy directed at the factors involved in the pathophysiology of the disease. For this purpose we evaluated a combination of clindamycin phosphate and salicylic acid in a non-irritating carrier.

NCT ID: NCT00355485 Completed - Acne Vulgaris Clinical Trials

Microdermabrasion for Acne

Start date: September 2006
Phase: Phase 2
Study type: Interventional

The purpose of this research project is to study the effect of micordermabrasion to try to improve the appearance of facial acne. The microdermabrasion machine is a hand-held device that directs pressurized aluminum oxide crystals at its target accompanied by a suction device. It is not yet clear how much improvement can be seen with these treatments or exactly how the skin's response causes these improvements. In this study, we are interested in learning how well microdermabrasion works to improve the symptoms of acne.

NCT ID: NCT00306371 Completed - Acne Clinical Trials

Comparison of Stacked-Pulses Vs. Double-Pass Treatments of Facial Acne With a 1450 Nm Laser

Start date: July 2004
Phase: N/A
Study type: Observational

Acne can be treated with a mid-infrared laser. We demonstrated safety and efficacy using lower energy settings in order to make the treatments less painful

NCT ID: NCT00280657 Completed - Acne Vulgaris Clinical Trials

Study on Safety and Efficacy of an Oral Contraceptive in Treating Acne Papulopustulosa

Start date: March 10, 2004
Phase: Phase 3
Study type: Interventional

The purpose of the study is to determine safety and efficacy of an oral contraceptive in treating acne papulopustulosa.

NCT ID: NCT00243542 Completed - Acne Vulgaris Clinical Trials

Phase IV Study to Gather More Information About the Safety of ACZONE Gel, 5% in Treating Subjects With Acne Who Have G6PD Deficiency

Start date: November 2005
Phase: Phase 4
Study type: Interventional

The purpose of this study is to gather more information about the safety of ACZONE Gel, 5% in treating subjects with acne who have certain blood disorders. ACZONE Gel, 5% is a prescription skin use (topical) medicine used to help treat acne in people 12 years and older. ACZONE Gel, 5% has been studied in approximately 4000 people and was shown to reduce the number of pimples and improve acne. The active drug ingredient in ACZONE Gel, 5% is dapsone. People with blood disorders called "G6PD deficiency", "methemoglobin reductase deficiency", and "hemoglobin M" have a higher chance of side effects with dapsone. G6PD is short for "glucose-6-phosphate dehydrogenase". It is an enzyme found in red blood cells, which carry oxygen to all parts of the body. G6PD helps the red blood cells to function normally. Some people have less G6PD in their red blood cells than the average person. This is called G6PD deficiency. Two treatments - ACZONE Gel, 5% and placebo - will be studied for comparison.

NCT ID: NCT00219570 Completed - Acne Vulgaris Clinical Trials

Dalacin-T Gel Post Approval Study

Start date: January 2005
Phase: Phase 4
Study type: Interventional

To investigate, in a comparison vs. Acuatim cream (nadifloxacin cream), the efficacy and safety of Dalacin T Gel (clindamycin phosphate gel) as a therapeutic medication for acne vulgaris in acne vulgaris patients, including children ages 13 and up, in order to clarify the clinical positioning of Dalacin T Gel.

NCT ID: NCT00211523 Completed - Acne Vulgaris Clinical Trials

Safety and Efficacy of MBI 226 2.5% and 5.0% Topical Acne Solutions in the Treatment of Acne

Start date: October 2000
Phase: Phase 2
Study type: Interventional

This study investigates the safety and efficacy of MBI 226 2.5% and 5.0% Acne Solutions, applied topically for six weeks, in the treatment of acne.

NCT ID: NCT00211497 Completed - Acne Vulgaris Clinical Trials

Safety and Efficacy of MBI 226 1.25% and 2.5% Topical Acne Solutions in the Treatment of Acne

Start date: January 2003
Phase: Phase 2
Study type: Interventional

This is a Phase II, randomized, vehicle-controlled, double-blind, multi center study to evaluate the efficacy and safety of topically applied MBI 226 1.25% and 2.5% Acne Solutions as anti-acne preparations in human subjects with facial acne vulgaris.

NCT ID: NCT00206895 Completed - Acne Vulgaris Clinical Trials

Photodynamic Therapy of Acne Vulgaris - a Randomized Blinded Controlled Study

Start date: November 2004
Phase: N/A
Study type: Interventional

The purpose of the study is to evaluated the efficacy and tolerability of methyl aminolevulinate and 5-aminolevulinic acid photodynamic therapy in patients with moderate to severe facial acne vulgaris in a randomized controlled and investigator blinded trial.