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Acne Vulgaris clinical trials

View clinical trials related to Acne Vulgaris.

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NCT ID: NCT05151055 Recruiting - Hormonal Acne Clinical Trials

Lactoferrin + Vitamin E + Zinc for Hormonal Acne

Start date: March 2, 2020
Phase: Phase 2
Study type: Interventional

We previously showed that twice daily intake of a combination of 100 mg lactoferrin, 11 IU vitamin E, and 5 mg zinc significantly reduced both inflammatory and non-inflammatory acne lesions compared to placebo control. In that study, females showed an overall better response compared to males in terms of total lesions. We speculated that the gender effect may be due to mitigation of the pre- menstrual flare-ups women have that lead to recurring acne, making them have a better response. The objectives of this study are: 1.) to characterize the efficacy and safety of 100 mg lactoferrin + 11 IU vitamin E + 5 mg zinc in the adult female population who suffer from hormonal acne, 2.) to determine whether the anti-acne effect is maintained after treatment stops.

NCT ID: NCT05080764 Recruiting - Acne Vulgaris Clinical Trials

Study to Evaluate the Safety and Efficacy of BF-200 ALA (Ameluz®) and BF-RhodoLED® in the Treatment of Moderate to Severe Acne Vulgaris With Photodynamic Therapy in Adults

Start date: December 10, 2021
Phase: Phase 2
Study type: Interventional

The aim of this study is to test the safety and efficacy of photodynamic therapy (PDT) for the medication Ameluz® performed with the PDT-lamp BF-RhodoLED® in comparison to the respective placebo treatment for moderate to severe Acne vulgaris.

NCT ID: NCT05069272 Recruiting - Acne Vulgaris Clinical Trials

Double-blinded, Vehicle Controlled Study to Evaluate Efficacy & Tolerance of Bakuchiol and Ethyl Linoleate on Acne

Start date: September 10, 2021
Phase: N/A
Study type: Interventional

Subjects will be assigned to a active cream or vehicle to compare the cosmetic effects. This will take place over a 12 week period.

NCT ID: NCT04648995 Recruiting - Acne Scar Clinical Trials

TheTreatment of Acne Scar Using UltraPulse CO2 Laser

Start date: December 11, 2020
Phase: N/A
Study type: Interventional

Purpose of the study is to assess the effect and evaluate topographic volume changes of UltraPulse at treating boxcar scars with different energy and the effect of UltraPulse at treating icepick scars.

NCT ID: NCT04596748 Recruiting - Acne Vulgaris Clinical Trials

Oral Probiotics on the Microbiome and Lipidome in Acne Vulgaris

Start date: May 11, 2020
Phase: N/A
Study type: Interventional

The purpose of this study is to determine how probiotics affect sebum production and gut health in those with acne vulgaris.

NCT ID: NCT04582383 Recruiting - Acne Clinical Trials

Comparative Effectiveness Study of Spironolactone Versus Doxycycline for Acne

Start date: March 30, 2022
Phase: Phase 4
Study type: Interventional

Acne is common illness of adolescents and young adults which is associated with substantial morbidity. While topical treatments are often sufficient for mild acne, moderate to severe acne often requires treatment with systemic medications such as oral antibiotics, hormonal therapies such spironolactone, and isotretinoin. Sebum overproduction is fundamental to the pathogenesis of acne with associated disordered keratinization and subsequent microbial colonization and inflammation resulting in the clinical manifestations of acne. Given the influence of hormones on sebum production, therapies that address these underlying hormonal factors such as spironolactone and oral contraceptive pills represent an underutilized treatment option for women with acne and could help decrease the use of long-term oral antibiotics in this patient population. The purpose of this trial is to evaluate the comparative effectiveness of spironolactone versus doxycycline hyclate (tetracycline class antibiotic) for women with acne.

NCT ID: NCT04538703 Recruiting - Acne Vulgaris Clinical Trials

Social Media Use of Acne Vulgaris Patients: Multicenter, Survey Work

Start date: March 1, 2020
Phase:
Study type: Observational

Acne Vulgaris is a chronic skin disease. However, chronic and repetitive due to the quality of life and psychological status of patients can affect. For this reason, patients carry out various research on their diseases on social media and follow programs on these issues in other media such as television and radio. However, there is no study on how much patients are interested in these publications, how much they trust them, and how they reach and organize information via social media. The aim of the study will be to clarify how and how patients with Acne Vulgaris use social media to obtain information about the diagnosis and treatment of their disease, the interaction of patient groups with each other, and how often social media is used, especially in which group of patients.

NCT ID: NCT04483063 Recruiting - Clinical trials for Arthroscopic Rotator Cuff Repair

Can Additional Preoperative Skin Cleaning on Face, Neck and Chest With Chlorhexidine Reduce Cutibacterium Acnes Contamination on Sutures in Arthroscopy Rotator Cuff Repair?

Start date: March 23, 2020
Phase: N/A
Study type: Interventional

The purpose of our study was to investigate whether preoperative skin cleaning on face, neck, and chest with chlorhexidine could reduce suture contamination of C. acnes in arthroscopic rotator cuff repair. We hypothesized that preoperative skin cleaning on face, neck and chest with chlorhexidine can reduce C. acnes contamination on sutures in arthroscopic rotator cuff repair.

NCT ID: NCT04214483 Recruiting - Acne Vulgaris Clinical Trials

A Pilot Study to Explore the Role of Gut Flora in Acne

Start date: March 2, 2020
Phase:
Study type: Observational

This study seeks to correlate microbiome sequencing data with information provided by patients and their medical records.

NCT ID: NCT04213638 Recruiting - Acne Vulgaris Clinical Trials

Trial of Single Microneedle Radiofrequency for Moderate‐to‐Severe Acne Vulgaris

Start date: November 15, 2019
Phase: N/A
Study type: Interventional

The purpose of the study is to testify the efficacy of treating moderate‐to‐severe acne vulgaris with Single Microneedle Radiofrequency, and provide evidence for the hypothesis that "whether Single Microneedle Radiofrequency therapy could be an alternative to photodynamic therapy for moderate to severe acne vulgaris."