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Acne Vulgaris clinical trials

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NCT ID: NCT02651012 Withdrawn - Acne Vulgaris Clinical Trials

Study to Evaluate the Efficacy and Safety of 1.5 mg/kg/Day of Sarecycline vs Placebo in the Treatment of Acne Vulgaris

SC1401
Start date: March 2015
Phase: Phase 3
Study type: Interventional

A Study to Evaluate the Efficacy and Safety Sarecycline in the Treatment of Acne Vulgaris.

NCT ID: NCT02647528 Withdrawn - Acne Vulgaris Clinical Trials

A Trial of Pulse Dyed Laser (Chromogenex Regenlite Transform) in the Treatment of Inflammatory Acne Vulgaris

Chromogenix
Start date: March 2016
Phase: Phase 4
Study type: Interventional

A Randomized, Blinded, Single-Centered, Placebo-Controlled Trial of Pulse Dyed Laser (Chromogenex Regenlite Transform) in the Treatment of Inflammatory Acne Vulgaris

NCT ID: NCT02100527 Withdrawn - Acne Vulgaris Clinical Trials

Study Of Safety, Tolerability And Effects Of PF-05175157 In Adults With Moderate To Severe Acne Vulgaris

Start date: April 2014
Phase: Phase 2
Study type: Interventional

This is a 6 week study to characterize the safety, tolerability and effects of PF-05175157 administered for 6 weeks in subjects with moderate to severe acne vulgaris.

NCT ID: NCT01785836 Withdrawn - Acne Vulgaris Clinical Trials

An Extension Study to Assess the Safety, Tolerability, Efficacy, and Treatment Adherence of Dapsone in Acne Vulgaris

Start date: March 2013
Phase: Phase 1
Study type: Interventional

This study will assess the safety, tolerability, and efficacy of dapsone in subjects with acne vulgaris following 12 weeks of treatment.

NCT ID: NCT01613924 Withdrawn - Acne Vulgaris Clinical Trials

Efficacy of Handheld Acne Heat Device

Start date: July 2013
Phase: Phase 4
Study type: Interventional

The aim of our study is to determine the time to resolution of individual acne lesions using a popular handheld heat based device in comparison to no treatment and to standard topical therapy with benzoyl peroxide in order to determine its effectiveness in the spot treatment of acne vulgaris. Patient satisfaction and potential side effects will be examined as well.

NCT ID: NCT01425320 Withdrawn - Acne Vulgaris Clinical Trials

Pharmacokinetics Study of Dapsone-Adapalene Fixed Combination Gel in Acne

Start date: January 2013
Phase: Phase 1
Study type: Interventional

This study will investigate the pharmacokinetics, safety and tolerability of dapsone and adapalene following topical administration of 2 formulations of dapsone/adapalene fixed combination gel, dapsone 5% gel (ACZONE®), and adapalene 0.3% gel (Differin®) in subjects with acne vulgaris.

NCT ID: NCT00814918 Withdrawn - Acne Vulgaris Clinical Trials

Topical 5-ALA-PDT With Blu-U Therapy Versus Topical 5-ALA With Pulse Dye Laser In Treating Recalcitrant Acne Vulgaris

Start date: February 2009
Phase: N/A
Study type: Interventional

The goal of this study is to compare how efficient two different types of PDTs are when used in combination with topical 5-ALA. The two types of PDT lights are Blu-U light and Candela V-beam Pulse Dye Laser.

NCT ID: NCT00613444 Withdrawn - Acne Vulgaris Clinical Trials

Photodynamic Therapy in the Treatment of Acne

Start date: February 2008
Phase: N/A
Study type: Interventional

The purpose of this research project is to study the effect of non-ablative (non-cutting) laser therapy, a technique that uses laser energy to try to improve the appearance of the skin. This type of laser treatment creates changes in a layer of the skin called the dermis without causing an open wound in the skin. The use of non-ablative laser therapy, together with application of a photo-sensitizer (substance that makes the skin more sensitive to light), may improve the appearance of acne. The idea behind the photo-sensitizer is that it is supposed to make the laser more effective than using just the laser alone. It is not yet clear how much improvement can be seen with these treatments or exactly how the skin's response causes these improvements. In this study, we are interested in learning how well such a laser works to improve the symptoms of acne, as well as how much the photo-sensitizer actually enhances the efficacy of the laser. The photo-sensitizing agent (Levulan Kerastick) and the non-ablative laser (LumaCare LC-122M non-coherent (multiple wavelengths) light source from LumaCare® Medical Products) are both FDA-approved. The Levulan Kerastick is approved for the treatment of another skin disease, not acne.

NCT ID: NCT00441805 Withdrawn - Acne Vulgaris Clinical Trials

The Treatment of Acne Vulgaris With Radiofrequency Device

Start date: November 2006
Phase: N/A
Study type: Interventional

Radiofrequency emmitting device, normaly used for thermage treatments will be used on 22 mild to moderate acne patients faces. The aim of the study is to check whether RF heating of subcutaneous and dermis will improve acne in needed patients.