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Acne Vulgaris clinical trials

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NCT ID: NCT05497323 Active, not recruiting - Acne Vulgaris Clinical Trials

Effectivity and Safety of Combination Cream of Salicylic Acid, Aqua Posae Filiformis, Niacinamide, Lipohydroxy Acid, Procerad and Zinc PCA

Start date: August 1, 2022
Phase: Phase 1
Study type: Interventional

This clinical study will compare the effectivity and safety of combination cream of Salicylic Acid, Aqua Posae Filiformis, Niacinamide, Lipohydroxy Acid, Procerad, and Zinc PCA as adjuvant therapy for acne vulgaris patients. These combination cream will be tested by mild to moderate acne vulgaris patients. Participants will be female patients aged 15-50 years old and divided into three groups. The control group (Group 1) will use Adapalene 0.1% cream only every night. Group 2 will use Adapalene 0.1% cream intermittently every two nights and the combination cream every morning. Group 3 will use Adapalene 0.1% cream every night and the combination cream every morning.

NCT ID: NCT05218486 Active, not recruiting - Acne Vulgaris Clinical Trials

Effect of Oral Isotretinoin on The Level of SerumYKL40 in Acne Vulgaris Patients

Start date: August 1, 2021
Phase: Phase 4
Study type: Interventional

The aim of the study is to evaluate the effect of oral isotretinoin on SerumYKL40 in acne vulgaris patients.

NCT ID: NCT04870489 Active, not recruiting - Acne Vulgaris Clinical Trials

Combined Treatment With CO2 Laser and Isotretinoin for Acne Scars

Start date: November 1, 2017
Phase: Phase 2
Study type: Interventional

Isotretinoin is an FDA-approved vitamin A metabolite for the treatment of severe acne; acne that does not respond to other treatments and has a tendency to cause scarring. Ablative laser treatment is another effective treatment against acne scarring. We believe that the combination of CO2 ablative laser treatment with oral isotretinoin for the treatment of scarring is not only safer but also more effective and leads to much more successful cosmetic results.

NCT ID: NCT04807179 Active, not recruiting - Acne Scars Clinical Trials

Clinical Study to Evaluate Alexandrite Laser for the Treatment of Acne Scars

Start date: March 8, 2021
Phase: N/A
Study type: Interventional

The intended use of the Alexandrite laser device used in this study is to assess the efficacy and safety of the Alexandrite laser device for the treatment of acne scars on skin types V and VI.

NCT ID: NCT04466527 Active, not recruiting - Acne Vulgaris Clinical Trials

Laser Treatment of Moderate to Severe Acne Vulgaris

Start date: May 20, 2021
Phase: N/A
Study type: Interventional

In this study, we are enrolling subjects with moderate to severe acne vulgaris and investigating the use of a commercially available laser in treating acne.

NCT ID: NCT03901417 Active, not recruiting - Acne Scars Clinical Trials

Comparison of 1550nm Fractional Laser Alone Versus in Combination With Microneedling for the Treatment of Acne Scars

Start date: June 1, 2019
Phase: N/A
Study type: Interventional

Acne scarring is an unfortunate consequence of inflammatory acne vulgaris that often leads to significant cosmetic and psychosocial impacts. Although there have been many advances in the treatment of acne scarring, it remains one of the greatest challenges in cosmetic and laser dermatology. There have been a multitude of studies establishing the efficacy of non-ablative fractional laser therapy for the treatment of atrophic acne scars, and it is widely regarded as one of the best available treatments. More recently, there has been a renewed interest in controlled, non-thermal dermal injury via microneedling devices in the treatment of atrophic acne scars. Where there is a gap in the literature, however, is in the evaluation of the combination of non-ablative fractional laser resurfacing with microneedling in the treatment of atrophic acne scars. The investigators' study will compare the safety and efficacy of using non-ablative fractional laser versus a combination of microneedling and non-ablative fractional laser for atrophic acne scars using a randomized, double-blind, split-face study. The investigators' aim is to further elucidate the pathogenesis of acne scarring and the best approaches for treatment. In doing so, the investigators will study a combination approach to this complex problem in order to better serve future patients.

NCT ID: NCT03900676 Active, not recruiting - Acne Vulgaris Clinical Trials

Efficacy and Safety Study of VB-1953 Topical Gel for Inflammatory Facial Acne Vulgaris

Start date: April 9, 2019
Phase: Phase 2
Study type: Interventional

A Phase 2, Multicenter, Randomized, Double-Blind, Vehicle Controlled, Dose-ranging Study in the Treatment of Acne Vulgaris,

NCT ID: NCT03818555 Active, not recruiting - Acne Vulgaris Clinical Trials

Sebacia Postmarket Study of Real-World Use

Start date: January 1, 2019
Phase: N/A
Study type: Interventional

Postmarket study of Sebacia Microparticles treatment during adoption into clinical use for patients with mild to moderate inflammatory acne vulgaris.

NCT ID: NCT02713607 Active, not recruiting - Acne Vulgaris Clinical Trials

Lipidome and Microbiome Profile of Acne

Start date: March 2016
Phase: Phase 1/Phase 2
Study type: Interventional

Lipidome and microbiome analysis in subjects with acne on doxycycline. Investigators will look at the skin lipidome, blood lipidome, gut micro biome and skin micro biome. Investigators will look at the changes between acne subjects and control participants, but also the changes that occur after the use of antibiotics and how this is altered.

NCT ID: NCT02395549 Active, not recruiting - Acne Vulgaris Clinical Trials

A Study to Determine the Efficacy of Topically Applied MTC896 Gel in Subjects With Acne Vulgaris

Start date: April 2015
Phase: Phase 2
Study type: Interventional

This study is designed to investigate the efficacy, safety and tolerability of MTC896 Gel in subjects with acne. In this study, MTC896 Gel will be applied at 3 concentrations, twice daily (bid) for 12 weeks and compared against a vehicle control.