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NCT02216864 Clinical Trial

Effect of Multiple Subcisions on Rolling Acne Scars

Acne Scars Clinical Trial

Official title:
Pilot Split Face Randomized, Evaluator Blinded Study on the Effect of Multiple Subcisions on Rolling Acne Scars

Clinical Trial Details — Status: Active, not recruiting

Administrative data
NCT number NCT02216864
Other study ID # STU97928
Secondary ID
Status Active, not recruiting
Phase N/A
First received
Last updated
Start date August 2014
Est. completion date December 2024

Study information
Verified date February 2024
Source Northwestern University
Contact n/a
Is FDA regulated No
Health authority
Study type Interventional

Clinical Trial Summary

The purpose of this study is to find out whether the use of multiple subcisions over several visits will improve the appearance of rolling acne scars compared to no treatment. This study was a pilot study designed to determine feasibility of this procedure.

Recruitment information / eligibility
Status Active, not recruiting
Enrollment 5
Est. completion date December 2024
Est. primary completion date December 2024
Accepts healthy volunteers Accepts Healthy Volunteers
Gender All
Age group 18 Years to 65 Years
Eligibility Inclusion Criteria: 1. Age 18 to 65 2. Have bilateral rolling acne scars on each side of their face 3. No active or ongoing acne. 4. The subjects are in good health 5. The subject has the willingness and the ability to understand and provide informed consent for the use of their tissue and communicate with the investigator. Exclusion Criteria: 1. Under 18 years of age 2. Pregnancy or Lactation 3. Subjects who are unable to understand the protocol or to give informed consent 4. Subjects with mental illness 5. Recent Accutane use in the past 6 months 6. Subjects prone to hypertrophic and keloidal scarring 7. Subjects reporting any blood diseases (HIV, Hepatitis, etc.) 8. Subjects reporting a history of Herpes (oral or genital)

Study Design

Related Conditions & MeSH terms

Intervention

Procedure:
• Multiple Subcision
At the start of the procedure, a straight vitrectomy knife will be inserted subdermally and will be slowly advanced parallel to the dermis. Rapid advancement and retraction of the needle under the scarred area in a lancing motion will be performed to abrade the underside of the dermis followed by side to side sweeping motions attempting to break any fibrous attachments to the deeper tissues.

Locations
Country Name City State
United States Northwestern University Feinberg School of Medicine, Department of Dermatology Chicago Illinois

Sponsors (1)
Lead Sponsor Collaborator
Northwestern University

Country where clinical trial is conducted

United States, 

Outcome
Type Measure Description Time frame Safety issue
Primary Change in acne scarring compared to baseline after treatments The change in acne scarring is measured using a quantitative global scarring grading system to compare baseline to the treatment. Baseline and 36 weeks
See also
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