Clinical Effect of Platelet Rich Plasma Combined With Laser on Scar

Acne Scar Clinical Trial

Official title:

Clinical Study on Efficacy and Safety of Platelet Rich Plasma Combined With Laser for Scar Treatment

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT02396290
• Other study ID #: 2012-0998
• Status: Completed
• Phase: N/A
• First received: March 9, 2015
• Last updated: March 17, 2015
• Start date: March 2013
• Est. completion date: September 2013

Study information

• Verified date: July 2013
• Source: Seoul National University Hospital
• Contact: n/a
• Is FDA regulated: No
• Health authority: Korea: Institutional Review Board
• Study type: Interventional

Clinical Trial Summary

Investigation of Clinical Effect of Platelet Rich Plasma Combined With Laser on Acne Scar

Description:

Platelet Rich Plasma may relieve the adverse effect of laser treatment. and it can be expected to improve acne treatment result.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 29
• Est. completion date: September 2013
• Est. primary completion date: September 2013
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: Both
• Age group: 19 Years to 40 Years

Eligibility

Inclusion Criteria:

• moderate to severe acne scar

Exclusion Criteria:

• taken procedures for acne scar within 6 months

• underlying diabetes mellitus, keloid, or malignancy

Study Design

Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Single Group Assignment, Masking: Double Blind (Subject, Outcomes Assessor), Primary Purpose: Treatment

Related Conditions & MeSH terms

• Acne Scar

Intervention

Procedure:
• fractional carbon dioxide laser with platelet rich plasma
fractional carbon dioxide laser followed by platelet rich plasma injection
• fractional carbon dioxide laser with NS
fractional carbon dioxide laser followed by normal saline injection

Locations

Country	Name	City	State
Korea, Republic of	Department of Dermatology, Seoul National University College of Medicine	Seoul

Sponsors (1)

Lead Sponsor	Collaborator
Seoul National University Hospital

Country where clinical trial is conducted

Korea, Republic of, 

References & Publications (1)

Tierney EP, Eisen RF, Hanke CW. Fractionated CO2 laser skin rejuvenation. Dermatol Ther. 2011 Jan-Feb;24(1):41-53. doi: 10.1111/j.1529-8019.2010.01377.x. Review. — View Citation

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Global assessment of acne scar	5-point grading of acne scar	12 weeks	No
Secondary	ECCA (échelle d'évaluation clinique des cicatrices d'acné)	quantitative analysis of acne scar	12 weeks	No
Secondary	adverse effect assessment	adverse effect assessment - erythema index, Epithelization Scale (0-12 point)	12 weeks	Yes