ACL Clinical Trial
Official title:
Tibial Tunnel Widening in ACL Reconstruction-Comparing Two Bioscrews: A Prospective Randomized Clinical Trial
Widening of the single tibial tunnel following ACL surgery with quadrupled hamstrings
autograft may contribute to failure of the graft and/or present technical challenges
secondary to bone loss in a revision setting (Getelman, 1999). As such, efforts should be
made to minimize the incidence and magnitude of tibial tunnel widening without sacrificing
the biomechanical properties of the graft construct. The purpose of this investigation is to
examine the tibial tunnel widening relationship between bioabsorbable interference screws
composed of poly-L-lactic acid (PLLA) alone and composite bioabsorbable interference screws
composed of poly-L-lactic acid embedded with beta tricalcium phosphate (PLLA+TCP) utilized as
tibial fixation devices.
Specifically the study has the following objectives: 1) To quantify the extent of tibial
tunnel enlargement at 3-, 6- and 12-months post ACL reconstruction with autogenous quadrupled
hamstring graft; 2) To determine if the incorporation of beta tricalcium phosphate to the
bioabsorbable interference screw alters the observed magnitude of tunnel widening; 3) To
hypothesize mechanisms for any observed differences between tibial fixation devices; and 4)
To correlate tibial tunnel widening with clinical outcome status. It is hypothesized that the
PLLA+TCP bioabsorbable interference screw will not be associated with a reduction in tibial
tunnel widening around the implant but rather between the implant and articular surface,
compared to the PLLA alone screw. It is also hypothesized that there will be no effect of
observed tunnel widening on clinical outcomes or graft failure rates.
n/a
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Withdrawn |
NCT01433718 -
Decreasing Knee Injury Risk Factors With Neuromuscular Training
|
N/A | |
| Recruiting |
NCT05395767 -
LIVing Donor Allograft for Anterior Cruciate Ligament Reconstruction Study
|
N/A | |
| Withdrawn |
NCT03670550 -
Dynamic ACL Brace: In Vivo Kinematics
|
N/A | |
| Recruiting |
NCT04586361 -
Prospective Analysis of Introperative RegenLab PRP and Hyaluronic Acid in Patients With Knee ACL Tear
|
Phase 4 | |
| Active, not recruiting |
NCT06167343 -
Comparison of Semitendinosus and Quadriceps Grafts for Anterior Cruciate Ligament Reconstruction
|
N/A | |
| Completed |
NCT03711734 -
Feasibility of Electro Auricular Acupuncture for Analgesia After ACL Surgery: The Feasibility of Patient Blinding and Effects on Early Postoperative Pain
|
N/A | |
| Recruiting |
NCT04137003 -
Laval University Rouge et or Post ACL Surgery Program Effectiveness
|
N/A | |
| Completed |
NCT05876013 -
Reduced Knee Flexion Strength 18 Years After ACL Reconstruction in Hamstring Group Compared to Patellar Tendon Group
|
||
| Completed |
NCT05048420 -
THE EFFECT OF RAMP LESION REPAIR ON RETURN TO SPORTS IN ANTERIOR CRUCIATE LIGAMENT RECONSTRUCTION
|
N/A | |
| Terminated |
NCT05878652 -
Playmaker 3D Printed Knee Extender
|
N/A | |
| Recruiting |
NCT05542563 -
Mindfulness and ACL Surgery
|
N/A | |
| Completed |
NCT02913404 -
ACL-reconstruction vs ACL-reconstruction With EAT
|
N/A | |
| Recruiting |
NCT05720949 -
Genicular Nerve Blocks for Anterior Cruciate Ligament Knee Surgery
|
Phase 4 | |
| Recruiting |
NCT04753424 -
Semitendinosus Graft as Meniscal Transplant
|
||
| Not yet recruiting |
NCT04721119 -
Comparing Adductor Canal Block and Adductor Canal Block-Local Infiltration Analgesia for Post-operative Pain Management
|
N/A | |
| Recruiting |
NCT03080402 -
Mechanical Perturbation Training for ACL Injury Prevention
|
N/A | |
| Recruiting |
NCT06194682 -
Anterior Cruciate Ligament Study
|
||
| Enrolling by invitation |
NCT05161221 -
Post Operative Pain Management Through Adductor Canal Block With Bupivacaine for ACL Reconstruction
|
Phase 3 | |
| Withdrawn |
NCT04086030 -
Blood Flow Restriction Following ACLR
|
N/A | |
| Recruiting |
NCT05121857 -
What is the Effect of Vision on Movement Control in Anterior Cruciate Ligament Reconstructed Patients 7 Months Post-surgery?
|