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Acid Reflux Esophagitis clinical trials

View clinical trials related to Acid Reflux Esophagitis.

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NCT ID: NCT02054637 Not yet recruiting - Clinical trials for Non-acid Reflux Esophagitis

Resolving Bile Reflux by Lanreotide in Patients With Roux-en-Y Gastrojejunostomy

Start date: April 2014
Phase: Phase 2
Study type: Interventional

Somatostatine induces a dose-dependent reduction of postprandial plasma cholecystokinin (CCK) secretion with a concomitant inhibition of postprandial gallbladder contraction, abolishing almost completely bile salts output from the gallbladder. Somatostatine is also known to decrease acid production with significant increase of intragastric pH. In this way, somatostatine could influence acid as well as non-acid reflux by decreasing gallbladder emptying and decreasing acid secretion. Purpose of the study is to evaluate the efficacy of lanreotide autogel 120 mg on symptoms and endoscopic lesions in patients with an endoscopic gastrointestinal reflux esophagitis that cannot be controlled with classic therapy.