Accommodation Disorders

Accommodative Insufficiency Clinical Trial

— AD  

Official title:

Using Accommodative Lag to Diagnose Accommodation Disorders

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT01329848
• Other study ID #: 1R15EY021021
• Status: Completed
• Phase: N/A
• First received: April 4, 2011
• Last updated: December 23, 2014
• Start date: December 2010
• Est. completion date: August 2013

Study information

• Verified date: December 2014
• Source: Western University of Health Sciences
• Contact: n/a
• Is FDA regulated: No
• Health authority: United States: Institutional Review Board
• Study type: Observational

Clinical Trial Summary

This project will develop clinically useful, objective measurements of accommodative insufficiency and fatigue using continuous autorefraction recordings. The development of these procedures will help vision care professionals diagnose and treat accommodative anomalies.

Description:

This project studies accommodative function, the ability to focus while doing near work. Visual discomfort symptoms, such as headaches, sore eyes, and blurred vision are commonly associated with prolonged reading or other near work. Researchers have long suspected accommodative dysfunction was involved but most clinical studies have failed to establish a relationship between weak accommodation and symptoms or reading impairments. Recent research, however, has found that clinical measure overestimate accommodative function and encourage the use of objective, autorefraction methods to measure and study accommodative weakness. This project will accomplish three goals. First, using autorefraction objective reliable procedures will be developed for measuring accommodative lag, the difference between the target location and where the eye is focused. Second, experiments will measure in real-time the impact of accommodative lag on reading fluency and visual discomfort systems. Third, studies will explore the role of the slow adaptive component in accommodative weakness. This work will lead to better methods for diagnosing and treating accommodative disorders.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 83
• Est. completion date: August 2013
• Est. primary completion date: December 2012
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: Both
• Age group: 18 Years to 30 Years

Eligibility

Inclusion Criteria:

• older adolescent and young adult

• skilled readers who attend school

• are skilled readers

• have heavy reading demands

Exclusion Criteria:

• Age > 30.

• Abnormal vergence system.

• Dry-eye.

• Uncorrected visual defects or significant ocular pathology.

• Learning disability or low IQ

• Medical conditions that might cause uncomfortable visual symptoms (e.g., migraine headaches, epilepsy, head trauma); sensory defects (e.g., deafness), or neurological conditions (e.g., stuttering) that could impair reading development or oral reading fluency.

• Somatosensory amplification.

• Systemic illness or medication associated with accommodative dysfunction.

Study Design

Observational Model: Cohort, Time Perspective: Prospective

Related Conditions & MeSH terms

• Accommodative Insufficiency
• Ill-sustained Accommodation

Locations

Country	Name	City	State
United States	Western University of Health Sciences	Pomona	California

Sponsors (2)

Lead Sponsor	Collaborator
Western University of Health Sciences	Southern California College of Optometry

Country where clinical trial is conducted

United States, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Accommodation Lag 5D	Lag will be measured at different viewing distances and durations using autorefraction. Accommodation error refers to the difference between the distance where the target is located and where the eyes focus. Lag refers error that is under focussed; lead is error that is over focussed. This distance is measured in diopters, or 1/meter.	3 week period	No
Secondary	Conlon Symptom Survey	Measures visual discomfort symptoms while doing near work. 23 item survey using a 4-point rating scale (never, occasionally, often, almost always). Total raw score reported on a range from 0 to 69 with higher scores indicating more frequent symptoms.	3 weeks	No