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Abuse Potential clinical trials

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NCT ID: NCT06247488 Completed - Abuse Potential Clinical Trials

Evaluation of Abuse Potential of HORIZANT Taken Alone and With Oxycodone in Healthy, Nondependent Recreational Opioid Users

Start date: January 31, 2022
Phase: Phase 4
Study type: Interventional

The purpose of this study is to assess the abuse potential of gabapentin enacarbil immediate release capsules taken alone and in combination with oxycodone in healthy adult, non-dependent, recreational opioid users.

NCT ID: NCT06097676 Completed - Abuse Potential Clinical Trials

An Abuse Potential Study of Orally Administered HORIZANT in Healthy, Non-dependent, Recreational Drug Users

Start date: September 28, 2021
Phase: Phase 4
Study type: Interventional

The purpose of this study is to assess the abuse potential of gabapentin enacarbil in healthy adult, non-dependent, recreational drug users.

NCT ID: NCT05319756 Completed - Abuse Potential Clinical Trials

Study Evaluating the Abuse Potential of NEURONTIN® in Healthy Non-drug Dependent, Recreational Opioid Users

Start date: April 30, 2021
Phase: Phase 4
Study type: Interventional

This will be a randomized, double-blind, double-dummy, placebo- and active-controlled, 6 treatment, 6-period crossover single-dose, Williams square design study in healthy male and/or female adult, non-drug-dependent recreational opioid users.

NCT ID: NCT05106153 Completed - Abuse Potential Clinical Trials

A Study to Determine the Abuse Potential of Seltorexant Compared to Suvorexant and Zolpidem

Start date: December 17, 2021
Phase: Phase 1
Study type: Interventional

The purpose of this study is to evaluate the abuse potential of seltorexant compared to placebo and two active comparators (zolpidem and suvorexant) in non-dependent, recreational sedative users.

NCT ID: NCT05053126 Completed - Abuse Potential Clinical Trials

Study Evaluating Abuse Potential of Lyrica® in Healthy Non-Drug Dependent Recreational Opioid Users

Start date: July 27, 2021
Phase: Phase 4
Study type: Interventional

This is a Phase 4 clinical study in healthy non-drug dependent recreational opioid users to assess the abuse potential of Lyrica when taken alone or in combination with oxycodone.

NCT ID: NCT04570436 Completed - Abuse Potential Clinical Trials

Evaluating the Abuse Potential of NEURONTIN® When Taken Orally in Healthy Non-drug Dependent Participants With Sedative Drug Abuse Experience

Start date: March 29, 2021
Phase: Phase 4
Study type: Interventional

This will be a randomized, double-blind, double-dummy, placebo- and active controlled, 5 treatment, 10 sequence, 5 period crossover single dose, Williams square design study in healthy adult, non drug dependent male and female participants with drug abuse experience with sedative drugs.

NCT ID: NCT03200080 Terminated - Abuse Potential Clinical Trials

A Study to Determine the Abuse Potential of Tozadenant Relative to D-Amphetamine and Placebo When Administered Orally in Healthy, Non-Dependent, Recreational Polydrug Users

Start date: September 18, 2017
Phase: Phase 1
Study type: Interventional

This will be a single-dose, randomized, double-blind, active- and placebo-controlled, double dummy, 6-way crossover study to determine the abuse potential of tozadenant relative to d-amphetamine and placebo, when administered orally in healthy non-dependent, recreational polydrug users with stimulant experience, under fed conditions. Each subject will participate in a medical Screening visit, a 4-day (3-night) qualification (drug discrimination) visit, six 3-day (2-night) treatment periods, and a follow-up visit.