Prefrontal Cortex and Abstract Thinking

Abstract Thinking Clinical Trial

Official title:

Neuropsychological and Anatomical Study of Concept Formation in Frontal Patients

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT01100281
• Other study ID #: C09-29
• Status: Completed
• Phase: N/A
• First received: April 7, 2010
• Last updated: December 8, 2011
• Start date: April 2010
• Est. completion date: April 2011

Study information

• Verified date: December 2011
• Source: Institut National de la Santé Et de la Recherche Médicale, France
• Contact: n/a
• Is FDA regulated: No
• Health authority: France: Afssaps - Agence française de sécurité sanitaire des produits de santé (Saint-Denis)
• Study type: Observational

Clinical Trial Summary

The capacity of concept formation is not well understood, even if a link is supposed with the functioning of the frontal lobes.

Our aim is to better understand the cognitive mechanisms underlying this function and to try to correlate the performance with atrophy of the frontal lobe in neurodegenerative diseases involving this region (frontotemporal lobar degeneration and progressive supranuclear palsy).

Recruitment information / eligibility

• Status: Completed
• Enrollment: 69
• Est. completion date: April 2011
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: Both
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

• informed consent signed

• MMSE> 20

• No contra indication to MRI

Exclusion Criteria:

• MMSE<20

Study Design

Observational Model: Case Control, Time Perspective: Prospective

Related Conditions & MeSH terms

• Abstract Thinking
• Concept Formation

Intervention

Behavioral:
• Neuropsychological examination
Examination including especially concept formation

Other:
• MRI
MRI performed in T1-weighted three dimensional sequence

Locations

Country	Name	City	State
France	Inserm U 975	Paris

Sponsors (1)

Lead Sponsor	Collaborator
Institut National de la Santé Et de la Recherche Médicale, France

Country where clinical trial is conducted

France,