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Clinical Trial Summary

The main aim of this study is to determine whether the levels of different inflammatory cytokines in the serum and BALF (bronchoalveolar lavage fluid) are relative to the severity and exacerbations of ABPA (allergic bronchopulmonary aspergillosis).


Clinical Trial Description

The study would record patients' medical data at baseline and follow them up for different period of time. Updated data would be recorded and blood( or BALF) of the patients would be drawn for tests or stored as whole blood or serum at -80℃ when patients visit the hospital. Then the cytokine (A panel set by the manufacturer) of the serum and BALF would be tested . The secretion ability of peripheral blood mononuclear cells would also be verified. The investigators would then analyze the data and see if any cytokine is relative to the exacerbation or other indicators of the severity of ABPA. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT03643185
Study type Observational
Source Shanghai Pulmonary Hospital, Shanghai, China
Contact Jin-fu Xu, MD
Phone +86 13321922898
Email jfxucn@163.com
Status Recruiting
Phase
Start date December 2014
Completion date May 4, 2021

See also
  Status Clinical Trial Phase
Completed NCT02853175 - Lung MRI and Allergic Broncho-pulmonary Aspergillosis in Cystic Fibrosis
Withdrawn NCT05903612 - Allergic Bronchopulmonary Aspergillosis Prescreening Study
Terminated NCT05667662 - Study to Evaluate Itraconazole Administered as Inhaled Dry Powder in Adults With Asthma and ABPA Phase 2
Withdrawn NCT04108962 - Benralizumab in the Treatment of Patients With Severe Asthma With ABPA Phase 4