Abortion, Complete Clinical Trial
Official title:
Pregnancy Dating Test - The Fall of hPL in Urine Over Time
Verified date | June 2020 |
Source | Guy's and St Thomas' NHS Foundation Trust |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Observational |
Earlier studies describe the half-life of hPL in serum as being ninety minutes and that the
hormone is excreted unchanged in urine; consequently, there is real potential to use the fall
in hormone levels in urine to monitor bleeding in pregnancy, the outcome of natural and
artificial abortions or placental health.
This study will focus on the fall of hPL following delivery by Caesarean section when women
have a urinary catheter in place and sampling urine is simple to achieve.
Status | Completed |
Enrollment | 11 |
Est. completion date | March 26, 2020 |
Est. primary completion date | March 26, 2020 |
Accepts healthy volunteers | No |
Gender | Female |
Age group | 18 Years to 52 Years |
Eligibility |
Inclusion Criteria: 1. The women is 18 years of age or older 2. She understands the patient information leaflet, trial requirements and has signed the consent form 3. The Caesarean delivery will be at GSTFT 4. Prepared for urine to be collected for up to when the urinary catheter is removed or six hours, whichever is sooner 5. Agrees for the demographic and medical history data to be collected. Exclusion Criteria: 1. Under 18 years of age 2. Unable to understand the patient information leaflet or consent to join the trial 3. The Caesarean delivery will not be at GSTFT 4. The women is not for urine to be collected 5. The women does not agree for demographic or history data to be collected. 6. The women has a haemorrhage greater than one litre during the Caesarean delivery |
Country | Name | City | State |
---|---|---|---|
United Kingdom | Guy's & St Thomas' NHS Foundation Trust | London | England |
Lead Sponsor | Collaborator |
---|---|
Guy's and St Thomas' NHS Foundation Trust | King's College Hospital NHS Trust |
United Kingdom,
Whittaker PG, Lind T, Lawson JY. A prospective study to compare serum human placental lactogen and menstrual dates for determining gestational age. Am J Obstet Gynecol. 1987 Jan;156(1):178-82. — View Citation
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | The rate of change in human placental lactogen concentration in urine post delivery by Caesarian section | Baseline and then 30, 60, 90, 120, 150, 180, 210, 240, 270, 300, 330 & 360 minutes after delivery of the baby by Caesarean section |
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