Clinical Trials Logo

Abnormalities, Multiple clinical trials

View clinical trials related to Abnormalities, Multiple.

Filter by:
  • Active, not recruiting  
  • Page 1

NCT ID: NCT04722315 Active, not recruiting - Kabuki Syndrome Clinical Trials

Study of Modified Atkins Diet in Kabuki Syndrome

Start date: April 1, 2021
Phase: Early Phase 1
Study type: Interventional

Animal models of Kabuki syndrome have showed a reversal of the cognitive phenotype with ketogenic diet. Modified Atkins diet is safer and easier tolerated than full ketogenic diet and still has the histone deacetylase inhibition believed to be responsible for the cognitive improvement. This study aims to examine a small number of adults with Kabuki syndrome before and after 12 weeks on a modified Atkins diet to determine if there is any cognitive improvement and if the diet can be tolerated.