Clinical Trials Logo
  1. Home
  2. Abdominal Wall Defect
  3. NCT04644965

Evaluation of the Motor Activity, Cardiopulmonary Performance Capacity and Quality of Life in Patients Born With a Congenital Abdominal Wall Defect

Abdominal Wall Defect Clinical Trial

Official title:
Evaluation of the Motor Activity, Cardiopulmonary Performance Capacity and Quality of Life in Patients Born With a Congenital Abdominal Wall Defect

Clinical Trial Summary

The two most common congenital abdominal wall defects (AWD) are gastroschisis and omphalocele. Prenatal detection is often possible and the defects are differentiated by the presence or absence of a sac around the eviscerated organs. A omphalocele occurs in 0.6-4.8 in 10,000 live births compared to 4.5 in 10,000 live births with gastroschisis. In the last years a rising incidence of gastroschisis has been shown worldwide. Both forms of AWDs necessitate early surgical intervention, mostly in one or two stages, and support at an intensive care unit in the first days of life. Additionally, patients need parenteral feeding in the first weeks of life. The outcome depends on the size of the defect and on the associated malformations. The literature about long-term outcome of these malformations is scarce. Some publications have reported long-term complications like redo-surgical procedures because of fascial gaps or umbilical or incisional hernias. Furthermore, stool irregularities, abdominal pain and several admission to the hospital due to ileus or sub-ileus have been described. Additionally, half of the patients are unsatisfied with the cosmetic result. Some other studies have shown that children born with an AWD have the same quality of life (QoL) compared with the healthy community. Nevertheless, patients with AWDs need a standardized, structured and multimodal long-time follow-up program to be able to detect any problems early and give advice to understand their illness in order to achieve the same QoL as healthy children. Therefore, the aim of this dissertation will be: - to prospectively assess the motor activity, cardiopulmonary performance capacity and QoL of patients treated with AWDs in our Department - to suggest a new standardized follow-up protocol for patients born with an AWD

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04644965
Study type Observational
Source Medical University of Graz
Contact
Status Completed
Phase
Start date October 5, 2020
Completion date May 31, 2023
View Details
See also
  Status Clinical Trial Phase
Recruiting NCT06086444 - Tranexamic Acid in Abdominoplasty. Phase 4
Completed NCT05579652 - Change in Fascial Tension in Open Abdomens
Terminated NCT03241719 - Novel Strategies to Improve Immunomodulation and Non-invasive Clinical Monitoring in VCA Early Phase 1
Recruiting NCT03765060 - The Efficacy and Security of the Small Stitch Technique in Emergency Surgery N/A
Recruiting NCT04580511 - Safety and Clinical Performance of a Biological Matrix Used in Abdominal Wall Reconstruction
Recruiting NCT03035617 - Study to Evaluate Reduction in Pain After Laparoscopic Hernia Repair With Mesh Soaked in Bupivacaine Solution N/A
Not yet recruiting NCT06367309 - ExtrAperitoneaL Plasty vs Intraperitoneal oNlay mEsh in Ventral Hernia Repair N/A
Completed NCT05061264 - Abdominal Wall Reconstruction With PVDF Mesh in the Setting of Active Infection N/A
Recruiting NCT03310905 - Abdominal Wall Transplant N/A
Completed NCT03960320 - Health Related Quality of Life of Patients With Abdominal Wall Defects
Recruiting NCT05308771 - To Investigate the Use of a New Syringe "Visual Pressure Control (VPC)" for Epidural Anesthesia in Children Surgery N/A
Recruiting NCT02416674 - Vascularized Composite Allotransplantation for Treatment of Abdominal Wall Defects Early Phase 1
Not yet recruiting NCT06364306 - oPen Versus RobotIc retrOmuscular Repair in Medium to Large Ventral Hernias N/A
Completed NCT05278117 - A Prospective Multicentre Study Evaluating the Outcomes of the Abdominal Wall Dehiscence Repair Using Posterior Component Separation With Transversus Abdominis Muscle Release Reinforced by a Retro-muscular Mesh - Filling a Step N/A
Completed NCT04947202 - Clinical Study on the Safety of SAFIL® MESH
Enrolling by invitation NCT03296475 - Intraoperative Biomechanics in Complex Abdominal Wall Reconstruction N/A
Completed NCT03702153 - The Use of Synthetic Mesh in Contaminated and Infected Abdominal Wall Repairs. A Long-term Prospective Clinical Trial N/A
Completed NCT05205213 - Stepwise for the Treatment of Lateral Incisional Hernias