Abdominal Pain Clinical Trial
Official title:
Safety and Efficacy of Carbon Dioxide Gas for Endoscopic Insufflation in Children
The goal of this clinical trial is to compare the efficacy and safety of air versus carbon dioxide gas insufflation for endoscopy in children. The main question[s] it aims to answer are: •to determine safety of CO2 Assess patient comfort (abdominal pain, flatulence and bloating) with CO2 use when compared to air.
In this study, children (6 months -18 years) undergoing all endoscopic procedures that includes an upper endoscopy including but not limited to Esophagogastroduodenoscopy (EGD/ upper endoscopy), EGD/ Colonoscopy, Endoscopic Retrograde Cholangiopancreatography (ERCP), Endoscopic ultrasound (EUS) e.t.c after appropriate consent, will be randomized 1:1 to either Air or CO2 gas for endoscopic insufflation. We will record demographics (name, age, sex, MRN, race/ethnicity), anthropometrics including weight, height/length, weight for length (WFL), WFL z score, BMI, BMI z score, indication/ reason for scope, other co-morbidities (other medical problems), personnel involved (faculty only, vs faculty + trainee), minute by minute end tidal CO2 levels, minute by minute minute ventilation levels, baseline blood pCO2, and blood pCO2 after each procedure. Pre and post procedure patient reported abdominal pain, bloating and flatulence. Pre and post procedure nurse assessed pain. Pre and post procedure vital signs. Patients will be randomized using a sealed envelope method by the endoscopy technician. Both patients and providers will be blinded to arm of enrollment. ;
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Completed |
NCT04682860 -
Management of Abdominal Pain in Acute Gastroenteritis Patients With Hyoscine Butylbromide
|
Phase 4 | |
| Not yet recruiting |
NCT05649891 -
Checklists Resuscitation Emergency Department
|
N/A | |
| Completed |
NCT02923245 -
POCUS Assessment of Bladder Fullness for Girls Awaiting Radiology-Performed Transabdominal Pelvic Ultrasound
|
N/A | |
| Completed |
NCT03318614 -
Bifidobacterium Infantis M-63 Improves Mental Health in Irritable Bowel Syndrome Developed After a Major Flood Disaster
|
Phase 2/Phase 3 | |
| Completed |
NCT02547857 -
Transvaginal Pelvic Ultrasound in the ED
|
N/A | |
| Completed |
NCT02676232 -
DARWeb: an Online Psychosocial Intervention for Children With Recurrent Abdominal Pain and Their Families.
|
N/A | |
| Completed |
NCT02197780 -
Head-to-head Comparison of Two Fecal Biomarkers to Screen Children for IBD
|
N/A | |
| Recruiting |
NCT00209807 -
Effect of Escitalopram vs. Reboxetine on Gastro-intestinal Sensitivity of Patients With Major Depressive Disorder
|
Phase 4 | |
| Terminated |
NCT01410071 -
Evaluation of Gastrointestinal Symptoms and Quality of Life in Patients With Sphincter of Oddi Dysfunction
|
N/A | |
| Terminated |
NCT01736280 -
Evaluating and Treating Potential Research Participants With Digestive Disorders
|
N/A | |
| Enrolling by invitation |
NCT04104867 -
Effectiveness of Prokinetic Agents in Improving Abdominal Discomfort at Colonoscopy
|
N/A | |
| Completed |
NCT03574727 -
Abdominal Cutaneous Nerve Entrapment Syndrome
|
||
| Completed |
NCT04614649 -
Right Iliac Fossa Treatment-Turkey Audit
|
||
| Completed |
NCT05438654 -
Improvement of Diagnostic Approach Using PoCUS for Right Upper Quadrant Abdominal Pain
|
N/A | |
| Completed |
NCT06423586 -
Effect of Lecithin-based Curcuma and Boswellia on Post-acute COVID-19 IBS
|
N/A | |
| Completed |
NCT03558009 -
Epidemiological Analysis for Hereditary Angioedema Disease
|
||
| Terminated |
NCT03148288 -
Vitamin D Supplementation in IBS
|
N/A | |
| Completed |
NCT03708874 -
Pain Management of Emergency Laparoscopic Cholecystectomy in Patients With Acute Cholecystitis
|
||
| Withdrawn |
NCT04408872 -
EUS vs EGD in Emergency Room Patients Referred for EGD
|
N/A | |
| Recruiting |
NCT02594774 -
Efficacy of Osteopathic Treatment in Function Abdominal Pain in Children and Adolescents
|
N/A |