The Effect of Intravenous Nalbuphine on PONV With Intrathecal Morphine in Abdominoplasty.

Abdominal Obesity Clinical Trial

Official title:

The Effect of Intravenous Nalbuphine on Postoperative Nausea and Vomiting With Intrathecal Morphine in Abdominoplastic Surgery.

Clinical Trial Details — Status: Recruiting

Administrative data

• NCT number: NCT03786562
• Other study ID #: 01003060501
• Status: Recruiting
• Phase: N/A
• Start date: March 8, 2019
• Est. completion date: September 2020

Study information

• Verified date: March 2019
• Source: Assiut University
• Contact: Mohamed Bakri, Prof
• Phone: +20882413201
• Email: mhbakri[@]gmail.com
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

How effectively intravenous nalbuphine can reduce the incidence of PONV after intrathecal administration of morphine in abdominoplastic surgery.

Recruitment information / eligibility

• Status: Recruiting
• Enrollment: 80
• Est. completion date: September 2020
• Est. primary completion date: March 2020
• Accepts healthy volunteers: No
• Gender: Female
• Age group: 20 Years to 50 Years

Eligibility

Inclusion Criteria:

• Patients undergoing abdominoplasty under spinal anesthesia

• American Society of Anesthesiologists (ASA) class I and II.

Exclusion Criteria:

• allergy to local anesthetics

• bleeding diatheses

• local infection or sepsis

Related Conditions & MeSH terms

• Abdominal Obesity
• Obesity, Abdominal

Intervention

Drug:
• Intrathecal Morphine
Group 1
• Intrathecal Morphine + Intravenous Nalbuphine
Group 2

Locations

Country	Name	City	State
Egypt	Assiut University Hospital	Assiut

Sponsors (1)

Lead Sponsor	Collaborator
Assiut University

Country where clinical trial is conducted

Egypt, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	postoperative nausea and vomiting	A verbal descriptive scale (VDS) was used to assess the severity of PONV. ( no nausea=0, severe nausea= 10); by postoperative nausea and vomiting scale which range (o no nasuea to 10 sever vomating).; A verbal descriptive scale (VDS) was used to assess the severity of PONV .	24 hours
Secondary	postoperative pain and puririts.	Visual analogue scale (VAS) pain scores (no pain = 0, worst possible pain = 10).	24 hours