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Abdominal Hernia clinical trials

View clinical trials related to Abdominal Hernia.

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NCT ID: NCT06014749 Recruiting - Regional Anesthesia Clinical Trials

Serratus Intercostal Block Versus Epidural Analgesia in Eventration: Prospective Observational Study

Start date: September 1, 2022
Phase:
Study type: Observational [Patient Registry]

Adequate pain control, rehabilitation and early postoperative recovery are currently the model to follow according to the recommended guidelines.In this project the main objective is to evaluate 2 different analgesic strategies both intraoperatively and postoperatively, one based on 1. Epidural analgesia and the other 2. Echoguided serratus intercostal block prior to surgical intervention in eventration or abdominal wall repair interventions. We conducted an observational study with a low level of intervention. Epidural analgesia prior to general anesthesia and serratus-intercostal block prior to general anesthesia) following the criteria applied in each case according to the operating room anesthesiologist until reaching the sample size and fulfilling the criteria of: abdominal eventration repair, over 18 years of age, ASA I-III. Signature of the IC.

NCT ID: NCT05906017 Recruiting - Abdominal Hernia Clinical Trials

Open Versus Robotic-assisted Ventral Hernia Repair, Short and Long-term Outcome

Start date: May 15, 2023
Phase: N/A
Study type: Interventional

In this randomized clinical trial, the investigators will compare the conventional open repair for hernia in the anterior abdominal wall with the robotic-assisted approach. 110 patients with midline abdominal wall defects will be randomized to either open or robotic-assisted surgery. The investigators will examine short and long-term complications through follow-up with clinical assessment as well as patient-reported outcome measures including pain, cosmetic appearance, and overall patient satisfaction. Furthermore, the investigators will study the difference in surgical stress response between the two methods measured from a variety of different biomarkers before and after the operation. A cost-effective analysis will be conducted for the robotic and open procedure.

NCT ID: NCT05792839 Not yet recruiting - Abdominal Hernia Clinical Trials

Abdominoplasty With Ventral Hernia Repair Versus Hernioplasty .

Start date: October 1, 2023
Phase: N/A
Study type: Interventional

Comparison between hernioplasty alone versus concomitant abdominoplasty with ventral hernia repair regarding efficacy and post-operative recurrence of hernia.

NCT ID: NCT05606757 Withdrawn - Ventral Hernia Clinical Trials

A Study to Evaluate Adverse Events and Effectiveness of OnabotulinumtoxinA in Participants Undergoing Open Abdominal Ventral Hernia Repair for the Achievement of Primary Fascial Closure Without the Use of Component Separation Technique

Start date: May 7, 2024
Phase: Phase 2
Study type: Interventional

Ventral hernias form when there is a loss of integrity of the abdominal wall muscles. Abdominal hernias can expand and can cause severe pain as the abdominal wall weakens. The purpose of this study is to evaluate the safety and efficacy of a range of onabotulinumtoxinA (BOTOX) doses to achieve primary fascial closure (PFC) without use of component separation technique (CST) in ventral hernia surgical repair. BOTOX is an investigational drug being developed for the treatment of ventral hernias. In this dose escalation study, participants will be placed in 1 of 3 cohorts. Cohort 1 will be randomized to receive placebo or 1 of 2 BOTOX doses, after which time Cohort 2 will be randomized to receive placebo or 1 of 3 BOTOX doses. Participants in Cohort 3 will be randomized to receive placebo or 1 of 3 BOTOX doses. Adult participants undergoing open abdominal ventral hernia repair will be enrolled. Around 200 participants will be enrolled in the study at approximately 20 sites in the United States. Participants will receive a single intramuscular injection of BOTOX Dose A, BOTOX Dose B, BOTOX Dose C, or placebo. There may be higher treatment burden for participants in this trial compared to their standard of care (due to study procedures). Participants will be followed for approximately 3 months after surgery and will receive a follow-up phone call 30 days (+/-) their last study visit. The effect of the treatment will be checked by medical assessments, blood tests, checking for side effects and completing questionnaires.

NCT ID: NCT05308771 Recruiting - Lung Diseases Clinical Trials

To Investigate the Use of a New Syringe "Visual Pressure Control (VPC)" for Epidural Anesthesia in Children Surgery

Start date: March 25, 2022
Phase: N/A
Study type: Interventional

Pediatric epidural anesthesia has emerged as a safe and effective regional anesthesia technique for providing intraoperative and postoperative analgesia in thoracic and abdominal surgery. The loss of resistance technique is the gold standard for the placement of the epidural. The VPC (visual pressure control) syringes developed by PAJUNK enable direct visualization of the introduction of the needle into the epidural space.

NCT ID: NCT05253586 Not yet recruiting - Abdominal Surgery Clinical Trials

Versius Or Laparoscopic Abdominal Hernia REpair

VOLARE
Start date: March 31, 2024
Phase:
Study type: Observational

This trial will compare laparoscopic and robotic-assisted abdominal hernia repairs, using the Versius® system. We will initially aim to recruit 60 patients (20 patients in the laparoscopic arm and 40 in the robotic arm) in order to assess the ergonomic impact of each modality on the operating surgeon. This aims to provide in vivo information on whether robotic surgery provides any advantages to the operating surgeon. This trial will also be used to assess the feasibility of recruitment to a future larger study, and any data collected will be used as pilot data.

NCT ID: NCT04947202 Completed - Ventral Hernia Clinical Trials

Clinical Study on the Safety of SAFIL® MESH

SAFIL_MESH
Start date: July 1, 2021
Phase:
Study type: Observational

Observational, Retrospective, Multi-center Clinical Study on the Safety of SAFIL® MESH in Patients Undergoing Reinforcement of Soft Tissues After Abdominal Wall Surgery or Other Fascial Defects

NCT ID: NCT04580511 Recruiting - Clinical trials for Abdominal Wall Defect

Safety and Clinical Performance of a Biological Matrix Used in Abdominal Wall Reconstruction

PMCF_AWR
Start date: November 4, 2020
Phase:
Study type: Observational

The general objective of the study is to confirm the medium/long-term safety and clinical performance of the CELLIS membrane used in abdominal wall reconstruction including, but not limited to, ventral hernia repair and stoma closure, and to identify emerging risks in comparison to the clinical data related to other types of fixation material. The present study will be a prospective multicentric non-randomized and noncontrolled trial involving 112 patients followed for 24 months. The study will be conducted in France in 3 investigational centres.

NCT ID: NCT04578340 Recruiting - Abdominal Hernia Clinical Trials

Long Term Outcomes Following Hernia Repair With Mesh

Start date: October 1, 2020
Phase:
Study type: Observational [Patient Registry]

The objective of this study is to establish the extent to which mesh improves quality of life and surgical outcomes following hernia repair.

NCT ID: NCT04435340 Completed - Abdominal Hernia Clinical Trials

Ventral Abdominal Hernia Repair With Self Adhering, Atraumatic Mesh

Start date: March 22, 2018
Phase: N/A
Study type: Interventional

Patients who underwent ventral abdominal hernia repair with self adhering, atraumatic mesh in sublay position are examined for their recurrence rate