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AAT Deficiency clinical trials

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NCT ID: NCT01851642 Recruiting - Clinical trials for Alpha-1 Antitrypsin Deficiency

Lung Disease and Its Affect on the Work of White Blood Cells in the Lungs

Start date: August 9, 2007
Phase:
Study type: Observational

The purpose of this study is to look at how Alpha-1-antitrypsin (AAT) deficiency and Cystic Fibrosis (CF) affect white blood cells in the lungs, called macrophages, and their ability to work.

NCT ID: NCT01810458 Completed - Liver Fibrosis Clinical Trials

Liver Fibrosis in Alpha-1 Antitrypsin Deficiency (Liver AATD)

Start date: October 2013
Phase:
Study type: Observational

We hypothesize that individuals with Alpha-1 Antitrypsin (AAT) deficiency have ongoing liver injury which is not detected by the usual blood tests used to look at liver function. This ongoing liver injury leads to cirrhosis in a significant number of adults with AAT deficiency.