Combination Therapy of Hydroxyurea With L-Carnitine and Magnesium Chloride in Thalassemia Intermedia

ß-Thalassemia Intermedia Clinical Trial

Official title: The Effect of Combination Therapy of Hydroxyurea With L- Carnitine and Magnesium Chloride on he-Matologic Parameters and Cardiac Function of β-Thalassemia Intermedia Patients.

Status Completed

Clinical Trial Summary

The purpose of this study is determination of the efficacy of combination of hydroxyurea with L-carnitine or magnesium in improving hematologic parameters and cardiac status in patients with β-thalassemia intermedia in comparison with hydroxyurea alone .

Clinical Trial Description

n/a

Study Design

Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Factorial Assignment, Masking: Double Blind (Subject, Caregiver), Primary Purpose: Treatment

Related Conditions & MeSH terms

• Beta-Thalassemia
• ß-Thalassemia Intermedia
• Thalassemia

• NCT number: NCT00809042
• Study type: Interventional
• Source: Shiraz University of Medical Sciences
• Status: Completed
• Phase: Phase 2
• Start date: June 2007
• Completion date: December 2007