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5-FU Containing Therapy Regimens clinical trials

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NCT ID: NCT02055560 Enrolling by invitation - Clinical trials for Metastatic Colorectal Cancer

Retrospective Evaluation of 5-FU Exposure Optimization in CRC Patients

Start date: January 2014
Phase: N/A
Study type: Observational

The primary objective of this study is to evaluate whether the management of colorectal cancer (CRC) patients with 5-fluorouracil (5-FU) exposure optimization testing reduces 5-FU related toxicities and improves outcomes compared to the current standard of care. A secondary objective is to characterize the variability of 5-FU levels among CRC patients managed with 5-FU exposure optimization testing and the impact of such management on 5-FU plasma levels and drug doses during the course of chemotherapy.