Laser Therapy to Treat the Dry Mouth of Sjogren's Syndrome

Status Recruiting

Clinical Trial Summary

This study was designed to test the efficacy and safety of low laser therapy to treat the xerostomia of patients with primary Sjogren's Syndrome.

Clinical Trial Description

The Sjogren's Syndrome is a disease that affects around 0,5% of the population and is mainly characterized for inflammatory involvement of salivary and lacrimal glands.

The xerostomia leads to low quality of life caused by dry sensations that can disturb the taste, the speaking, the swallow and chewing functions in the affected patients. The absent saliva can cause increase of dental caries and decays.

Until now, there is no effective treatment that increases the amount of saliva and the patients have low improvements with cholinergic drugs such as pilocarpine and cevimeline. These drugs can cause unpleasant collateral effects. ;

Study Design

Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Single Blind (Outcomes Assessor), Primary Purpose: Treatment

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT02066896
Study type	Interventional
Source	Federal University of São Paulo
Contact	Tania A Fidelix, investigator
Phone	55 11 991346992
Email	fidelixtania@gmail.com
Status	Recruiting
Phase	Phase 3
Start date	May 2014
Completion date	November 2016

View Details

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