Pilot Study of Triphala and Rubia Cordifolia on Gut Microbiome and Skin

Wrinkles Clinical Trial

Official title: Pilot Study on the Effects of Oral Triphala and Rubia Cordifolia on the Gut Microbiome and Skin Biophysical Properties

Status Completed

Clinical Trial Summary

Few studies have assessed the effects of Triphala and Rubia Cordifolia from a skin biophysical perspective. Here, we aim to understand how these herbs can modulate the skin's barrier properties and the gut microbiome.

Clinical Trial Description

Herbal supplements such as Rubia cordifolia and Triphala [a mix of Emblica officinalis (Amalaki), Terminalia bellerica (Bibhitaki), and Terminalia chebula (Haritaki)] are commonly used for skin based treatments in India. However, the scientific evidence for their specific effects on the skin are scant. Rubia cordifolia is a root that is used in skin care for pigmentation and inflammation.1 Triphala is thought to have antioxidant properties and reduce inflammation in general. Herbs have been shown to modulate the gut microbiome, as previous studies have suggested that triphala may modify the gut microbiome.2

However, few studies have assessed the effects of these herbs from a skin biophysical perspective. Here, we aim to understand how these herbs can modulate the skin's barrier properties and the gut microbiome. ;

Related Conditions & MeSH terms

• Erythema
• Facial Brrightness
• Facial Shine
• Facies
• Sebum Production
• Stool Microbiome
• Transepidermal Water Loss
• Wrinkles

• NCT number: NCT03477825
• Study type: Interventional
• Source: University of California, Davis
• Status: Completed
• Phase: N/A
• Start date: March 12, 2018
• Completion date: January 25, 2019