CT-based Model for Predicting Prolonged Weaning in Patients With Abdominal Trauma

Wounds and Injuries Clinical Trial

Official title:

CT-based Model for Predicting Prolonged Weaning From Mechanical Ventilation in Patients With Abdominal Trauma: a Retrospective Cohort Study

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT06339073
• Other study ID #: 2021NZKY-045-01
• Status: Completed
• Start date: October 1, 2023
• Est. completion date: February 5, 2024

Study information

• Verified date: March 2024
• Source: Jinling Hospital, China
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

Critically ill patients often require tracheal intubation for mechanical ventilation, and timely weaning is crucial for airway management and reducing complications. However, there is currently a lack of an effective tool to predict weaning time in critically ill patients. This retrospective study established an effective nomogram model for predicting the time of weaning from mechanical ventilation in abdominal trauma patients by considering multiple perspectives. The model has been validated and demonstrated good performance in terms of discrimination, calibration, and clinical utility. Moreover, the model can effectively predict the prognosis of critically ill patients. The findings of this study have important implications for guiding respiratory management in clinically critically ill patients, particularly trauma patients.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 1023
• Est. completion date: February 5, 2024
• Est. primary completion date: December 15, 2023
• Gender: All
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

• (1) with information on survival status and time;

• (2) aged 18-80 years;

• (3) admitted to ICU;

• (4) with abdominal CT performed within 1-week post-trauma;

• (5) use of mechanical ventilation.

Exclusion Criteria:

• (1) low-quality CT images;

• (2) history of mental illness.

Related Conditions & MeSH terms

• Abdominal Injuries
• Ventilation Therapy; Complications
• Wounds and Injuries

Intervention

Device:
• mechanical ventilation
Abdominal trauma patients were treated with mechanical ventilation according to their conditions.

Locations

Country	Name	City	State
China	the General Surgical Department of Jinling Hospital	Nanjing	Jiangsu

Sponsors (1)

Lead Sponsor	Collaborator
Jinling Hospital, China

Country where clinical trial is conducted

China, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Prolonged mechanical ventilation	Prolonged mechanical ventilation was defined as length of mechanical ventilation >7 days	through whole hospitalization of each participant, an average of 25 days