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Wounds and Injuries clinical trials

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NCT ID: NCT04592679 Completed - Clinical trials for Spinal Cord Injuries

Cost-Effectiveness Analysis of a Rehabilitation Protocol With FES Cycling in Persons With Complete SCI

Start date: January 1, 2015
Phase: N/A
Study type: Interventional

20 patients were recruited by two hospitals (AOUP and AOUC) in Italy from January 2015 to January 2018. The participants have been addressed to two different groups: the ones recruited by the AOUP were submitted to an experimental protocol of rehabilitation with FES Cycling, the ones recruited by the AOUC were submitted to a standard protocol of manual mobilization. The primary outcome was the thigh circumferences measured at 4 different levels (5-10-15-20 cm) from the superior margin of the patella, while the secondary outcomes were the muscle tone evaluated with Modified Ashworth Scale (MAS) and the sensation of pain registered with International Spinal Cord Injury - Pain Basic Data Set (ISCI-P). From these outcomes the Quality Adjusted Life Years (QALYs) was obtained. The costs of the two treatments were calculated through a consultation process with the Competent Offices of the two hospitals. The QALYs and the costs were used to calculate the Incremental Cost-Effectiveness Ratio (ICER) in order to verify the cost-effectiveness ratio of the two treatments.

NCT ID: NCT04592575 Completed - Clinical trials for Brain Injuries, Traumatic

Determining the Incidence of Vestibular Dysfunction in Traumatic Brain Injury Patients

Start date: December 15, 2020
Phase:
Study type: Observational

The purpose of this study is to determine the incidence of vestibular dysfunction in traumatic brain injury patients admitted to acute inpatient rehabilitation. This study also seeks to validate the AbilityLab Vestibular Screening Tool (AVeST) and the AVeST+, tools designed to quickly screen individuals for vestibular dysfunction following traumatic brain injury.

NCT ID: NCT04592328 Completed - Clinical trials for Surgical Site Infection

Sternal Wound and Aortic Graft (SWAG), an Observational Cohort Study.

SWAG
Start date: October 12, 2020
Phase:
Study type: Observational

The aim of this study is to systematically explore the perioperative presence of P acnes in all layers of sternal wound incision as well as contamination of graft material and prosthetic valves during primary operation. Secondly, to compare if different regimes of antibiotics affects the bacterial growth. Cultures will be taken from the skin, subcutaneous, and from the implanted valve prostheses with a rayon swab.Graft and Felt material will, after being pressed subcutaneous for 15 sec, placed into prepared sterile bottles containing broth for aerobe and anaerobe cultures. Surgical gloves will be cultured.

NCT ID: NCT04590911 Completed - Aging Clinical Trials

Effectiveness of Multimodal Cognitive Rehabilitation for Traumatic Brain Injury Sustained During Older Adulthood

Start date: September 1, 2012
Phase: N/A
Study type: Interventional

In a worldwide context of accelerated demographic aging, traumatic brain injury (TBI) in older adults has become a public health problem. TBI incidence grows following an exponential curve as people get older, increasing the occurrence of TBI in ageing individuals. Rehabilitation programs used in clinical settings have generally been developed for younger adults, and their efficacy with older adults who sustain a TBI has not been evaluated. The investigators have tailored a modular cognitive rehabilitation program for individuals who sustain a TBI in older adulthood, the Cognitive Enrichment Program (CEP), by adapting approaches which have shown to be effective in normal ageing and with other neurological conditions. The aim of the study is to evaluate the effectiveness of the CEP in adults having sustained a TBI during later adulthood. Specific objectives are to evaluate the effectiveness on memory, executive functions, psychological well-being and daily life activities using psychometric tests, self-reported questionnaires, and daily life-like tasks. The investigators hypothesize that memory and executive functions training included in the CEP will result in an improvement in both psychometric and self-reported scores in a trained group of older individuals with TBI, whereas this will not be the case for a comparable TBI group who did not receive the CEP intervention.

NCT ID: NCT04589780 Completed - Risk Reduction Clinical Trials

Is There a Relationship Between the Risk of Injury and Posture in Wrestlers?

Start date: October 10, 2020
Phase:
Study type: Observational

This study was planned to investigate the relationship between the risk of injury and posture in wrestlers. The study will be included male wrestlers. The spine posture and flexibility of the athletes will be measured during standing position with the Idiag M360® brand Spinal Mouse (SM), while the overall body posture will be measured from the anterior and lateral sides using the New York Posture Analysis Method (NYPAM). Injury risks of the athletes will be evaluated by Functional Movement Screen (FMS) which was consisting of seven basic movement patterns.

NCT ID: NCT04587102 Completed - Burn Injury Clinical Trials

Whole Body Vibration Training for Diabetic Patients With Burn Injury

Start date: January 10, 2019
Phase: N/A
Study type: Interventional

Burn injury as well as diabetes mellitus (DM) induce physical functional and psychological impairments. Lower limb burn involving Foot are still a challenging heath condition because of its important sensory role. Balance is disturbed either in patients with lower limb burn injury or diabetic patients. This study aime to compare between the effects whole body vibrational training and Yoga exercises on postural balance, and Activities-specific Balance Confidence in in type II diabetic Patients with foot burn

NCT ID: NCT04586712 Completed - Recovery Clinical Trials

Efficacy of a Controlled Short-term Trial of Cannabidiol (CBD) Ingestion on Reducing Symptomatic Response and Facilitating Recovery After Induced Muscle Injury

Start date: March 1, 2021
Phase: Phase 2
Study type: Interventional

The study aims to determine the efficacy of a controlled short-term trial of CBD ingestion for reducing symptomatic response and facilitating recovery following induced muscle injury. A double-blind, randomized, three-arm study design will be used and participants will be randomly assigned to either a high dose (n=15), low dose (n=15), or vehicle control group (n=15). The clinical outcomes include measures of muscular pain and disability along with measures of pain-related fear and anxiety.

NCT ID: NCT04584554 Completed - Clinical trials for Brain Injuries, Traumatic

Enhancing the Transition From Hospital to Home for Patients With Traumatic Brain Injury and Families

R03
Start date: February 17, 2021
Phase: N/A
Study type: Interventional

Despite high risks of readmission and complex medical needs, there are no transitional care standards in the U.S. for patients with moderate-to-severe traumatic brain injury (TBI) discharged home from acute hospital care without inpatient rehabilitation. To enhance the standard of TBI care, we will develop and refine a patient- and family-centered TBI transitional care intervention that addresses specific needs and preferences for patients with TBI (age < 65 years) and families and will assess the feasibility, acceptability, and preliminary efficacy of the intervention.

NCT ID: NCT04582747 Completed - Acute Kidney Injury Clinical Trials

Acute Kidney Injury - Biomarkers in Major Abdominal Surgery

AKI-BioMAS
Start date: July 3, 2018
Phase:
Study type: Observational

To validate Urinary Biomarkers for the prediction of AKI in major abdominal surgery patients

NCT ID: NCT04580875 Completed - Clinical trials for Penetrating Abdominal Trauma

Role of Minimally Invasive Surgery in Management of Penetrating Abdominal Trauma in Children

MISinPAT
Start date: January 2015
Phase: N/A
Study type: Interventional

Exploratory laparotomy has been traditionally used for managing penetrating abdominal trauma (PAT). Currently, minimally invasive surgery (for diagnosis and treatment purposes) is a well-established and rapidly growing modality for dealing with penetrating abdominal trauma in stable children. Herein, we aimed to evaluate the effectiveness and outcomes and emphasize the importance of timely intervention by minimally invasive surgery for PAT possessing the potential to violate the peritoneum in stable pediatric victims. This prospective study was carried out on 102 hemodynamically stable pediatric cases with highly suspicious penetrating abdominal trauma (caused by gunshot, stab, & accidental stab), admitted and managed by minimally invasive surgery (laparoscopy & laparoscopic-assisted procedures). Information recorded for analysis included demographic data, anatomical location of injury, organs affected, operative findings, operative time, need for conversion to laparoscopic-assisted approach, length of stay, complications, missed injury, and mortality rate. A total of 102 pediatric cases with highly suspicious penetrating abdominal trauma (PAT) were managed by minimally invasive surgery (MIS). They were 62 males and 40 females with mean age of 7.3±0.6 years (range, 1-14 years). They included 39 cases of gunshot, 30 cases of stab abdomen, and 33 cases of accidental stab. In this study, there was 100% accuracy in defining the injured organs with zero percent missed injuries in addition to effective therapeutic potential as regard the role of minimally invasive surgery in management of penetrating abdominal trauma in children. Type of Study: Prospective cohort study