Wound Heal Clinical Trial
Official title:
Assessment of Bone Healing After MTA and PRF Application in Periapical Lesions By Using CBCT
A total of 40 periapical lesions from the 33 patient undergoing apical surgery were randomly
selected from December 2016-November 2017. Patients were informed about the surgical
procedure and signed a consent form. Groups were divided in to 4; as control, MTA (mineral
trioxide aggregate), PRF (platelet rich fibrin) and MTA+PRF groups. Apical resection was
performed in all groups. No other interventions were made to the control group.
Routine radiographs were taken in the 1st. 3th and 6th months. In the (approximately) 12th
month of the procedures computerized tomography scans were taken. Primary healing of the
periapical tissues were evaluated and the outcomes were measured. Patients have still been
under control for the long term outcomes of the study.
44 apically infected periapical lesions were decided to enroll to the study from December
2016-November 2017. However; a total of 40 periapical lesions undergoing apical surgery were
recruited for the planned clinical trial in the end. The study was conducted under randomized
controlled protocol. Patients were informed about the surgical procedures and signed a
consent form. The anticipated outcomes, possible risks and benefits of the study as well as
the alternative treatment options were explained to the patients.
Groups were designed to have 10 patients in each and randomly divided into four as; control,
MTA, PRF and MTA+PRF. Apical resection was performed in all groups. No other interventions
were made to the control group.
Routine radiographs were taken in the 1st. 3th and 6th months. In the 12th month of the
procedures computerized tomography (CT) scans were taken. Primary healing of the periapical
tissues were evaluated according to the volumes and the densities of the lesions. Outcomes
were measured. Comparison between the initial and the last 3D CT scan volumes were made by
medical image processing software (MIMICS, Belgium). Patients have still been under control
for the long term outcomes of the study.
;
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Completed |
NCT05023135 -
DeepView SnapShot Portable (DV-SSP): Device Training Study
|
||
| Recruiting |
NCT03459547 -
Soft Peri-implant Tissue Around Different Abutment Materials
|
N/A | |
| Recruiting |
NCT05608187 -
Evaluating Safety and Biological Effect on Wound Healing of ILP100-Topical in Subjects With Diabetic Foot Ulcers
|
Phase 2 | |
| Active, not recruiting |
NCT03649308 -
Negative Pressure Wound Therapy Compared to Traditional Care After Skin Grafting
|
N/A | |
| Recruiting |
NCT04596124 -
Effectiveness and Tolerability of Fitostimoline Plus Cream and Gauze vs Connettivina Bio Plus Cream and Gauze
|
N/A | |
| Completed |
NCT03285542 -
Prospective Randomized Trial of Dermabond Prineo in Total Knee Arthroplasty
|
N/A | |
| Recruiting |
NCT05689775 -
Reconstruction After Abdominoperineal Resection With Robot-assisted Harvest of VRAM Flap
|
||
| Recruiting |
NCT05474911 -
PILONIDAL SINUS: CONVENTIONAL CARE VERSUS NEGATIVE PRESSURE THERAPY.
|
N/A | |
| Recruiting |
NCT04849143 -
The Effectiveness of Stingless Bee Honey (Kelulut Honey) Versus Gel in Diabetic Wound Bed Preparation
|
N/A | |
| Completed |
NCT03596112 -
The Difference in Wound Size Reduction Comparing Two Frequently Used Wound Dressings in Everyday Care
|
N/A | |
| Recruiting |
NCT05169814 -
Micro/Nanobubbles (MNBs) for Treatment of Acute and Chronic Wounds
|
Early Phase 1 | |
| Completed |
NCT04545476 -
Enhanced Secondary Intention Healing vs. Standard Secondary Intention Healing in Mohs Surgical Defects on the Head and Distal Lower Extremities
|
N/A | |
| Completed |
NCT06020157 -
Comparison of Simple and Continuous Suture Techniques in Oral Surgery
|
N/A | |
| Recruiting |
NCT05133570 -
Study Evaluating the Effectiveness of Treatment With Vista Care®, in Arterial Ulcers of the Lower Extremities
|
||
| Recruiting |
NCT04901325 -
Baricitinib in the Treatment of Adults With Pyoderma Gangrenosum (PG)
|
Phase 2 | |
| Withdrawn |
NCT03668665 -
Influencing Wound Healing Through the Application of Hyaluronic Acid With Perfluorodecalin and Physalis Angulata Extract After Split Skin Removal From the Thigh - A Study in "Split Wound Design"
|
Phase 3 | |
| Completed |
NCT03703479 -
Effect of A-PRF After Removal of Wisdom Teeth
|
N/A | |
| Recruiting |
NCT03204851 -
Microlyte Dressing in the Management of Wounds
|
N/A | |
| Recruiting |
NCT06117436 -
Impact of Cilostazol Versus Cilostazol and Selenium Combination on the Healing of Diabetic Foot Ulcer Patients
|
Phase 2/Phase 3 | |
| Completed |
NCT05618912 -
Scar Appearance After Postoperative Hydrocolloid Dressing Versus Standard Petrolatum Ointment
|
N/A |