Clinical Trials Logo
  1. Home
  2. Williams Syndrome
  3. NCT01864304

Fat Distribution and Glucose Metabolism in Williams Syndrome

Williams Syndrome Clinical Trial

Official title:
Characterization of Fat Distribution and Glucose Metabolism in Individuals With and Without Williams Syndrome

Clinical Trial Summary

Williams Syndrome (WS) is a genetic syndrome with features that may include vascular stenoses, neuro-developmental changes, and a variety of endocrine and metabolic abnormalities, including impaired glucose metabolism and abnormal body composition. Approximately 75% of adults with WS have impaired glucose tolerance or diabetes on oral glucose tolerance testing (OGTT). In addition, clinical observations and preliminary data suggest increased overall body fat in these individuals, as well as a relative increase in fat deposition in the lower extremities. However, glucose and lipid metabolism in WS remain incompletely characterized. The purpose of the current study is to carefully describe glucose metabolism and lipid parameters in people with WS.

Clinical Trial Description

n/a

Study Design

Observational Model: Cohort, Time Perspective: Cross-Sectional

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT01864304
Study type Observational
Source Massachusetts General Hospital
Contact
Status Completed
Phase N/A
Start date December 2013
Completion date February 2016
View Details
See also
  Status Clinical Trial Phase
Completed NCT00004351 - Study of Phenotype and Genotype Correlations in Patients With Contiguous Gene Deletion Syndromes N/A
Completed NCT03758651 - Williams Syndrome Strength, Hormones, Activity & Adiposity, DNA Programming, Eating Study
Enrolling by invitation NCT03836300 - Parent and Infant Inter(X)Action Intervention (PIXI) N/A
Completed NCT02212314 - Response Inhibition Training for Children With Williams Syndrome N/A
Recruiting NCT00768820 - The Psychiatric and Cognitive Phenotypes in Velocardiofacial Syndrome Phase 4
Recruiting NCT04610424 - Cooperative Parent Mediated Therapy in Children With Fragile X Syndrome and Williams Syndrome N/A
Recruiting NCT02706639 - Williams Syndrome (WS) and Supravalvar Aortic Stenosis (SVAS) DNA and Tissue Bank
Completed NCT02692846 - WS-SAVE Study (Williams Syndrome Skin and Vessel Elasticity Study)
Recruiting NCT06315699 - Clemastine Fumarate in the Treatment of Neurodevelopmental Delays in Williams Syndrome Phase 3
Recruiting NCT01793168 - Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford
Recruiting NCT01132885 - Defining the Brain Phenotype of Children With Williams Syndrome
Enrolling by invitation NCT05430763 - Motor Deficits and Signal Conduction in Individuals With Williams Syndrome
Recruiting NCT02840448 - Impact of Elastin Mediated Vascular Stiffness on End Organs
Recruiting NCT03827525 - Cognitive and Behavioral Therapy of Anxiety in Williams Syndrome
Completed NCT04807517 - Buspirone Treatment of Anxiety in Williams Syndrome Phase 4
Recruiting NCT06087757 - Clemastine Treatment in Individuals With Williams Syndrome Phase 3
Completed NCT00013962 - Vitamin D Metabolism and the Williams Syndrome N/A