White Spot Lesion Clinical Trial
Official title:
Clinical Evaluation of White Spot Lesions Treated by S-PRG Coating Material and Resin Sealants in Comparison With Resin Infiltration by Using Spectrophotometer and Laser Fluorescence. (A Randomized Controlled Trial) (WSLs)
Randomized with (1:1) prospective, double-blind, controlled trial. Subjects will be randomized to receive S-PRG and the control group receives ICON.
Interventions: - All the procedures will be performed by the same clinician. DIAGNOdent will be used to assess the fluorescence loss of WSLs and the adjacent sound enamel. WSLs in permanent teeth will be treated according to the manufacturer's instructions with: - Group I (Control group): 20 teeth will be treated with ICON. - Group II ( EXPERIMENTAL) : 20 teeth will be treated with PRG BarrierCoat. Observation: - The treatment methods will be assessed immediately after the intervention, 3 months,6 months, and one year. The data will be collected for evaluation of the difference in color and fluorescence loss between the treatment groups, by using DIAGNOdent devices, over different time intervals. Ethical considerations: The research protocol is approved by the ethical committee, Faculty of Dental Medicine, Al-Azhar University and the enrolled patients should sign a written consent form. ;
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Completed |
NCT05710874 -
A Prospective, Randomized, Clinical Study on the Effects of CPP-ACP-paste, Fluoride and a Combination on the Evolution of White Spot Lesions in Orthodontic Patients After Debonding.
|
N/A | |
| Completed |
NCT04107012 -
Evaluation of Enamel Demineralization During Clear Aligner Orthodontic Treatment
|
N/A | |
| Active, not recruiting |
NCT04342858 -
Prospective Randomized Controlled Trial for Prevention of Demineralization During Fixed Orthodontic Treatment
|
Phase 2 | |
| Recruiting |
NCT05989750 -
Air-polishing With Erythritol During Orthodontic Tretament
|
N/A | |
| Completed |
NCT06200129 -
İmportance of Scattered White Spots Detected in the Duodenum and Their Relationship wıth Zonulin
|
N/A | |
| Not yet recruiting |
NCT03976583 -
Remineralization Potential of Pearl Powder Compared to CPP-ACP on Enamel White Spot Lesions
|
Phase 2 | |
| Not yet recruiting |
NCT06051981 -
White Spot Lesions Treatment in Orthodontic
|
Phase 4 | |
| Not yet recruiting |
NCT04422860 -
Remineralization Efficacy of Gum Arabic Varnish.
|
Phase 2/Phase 3 | |
| Completed |
NCT04560478 -
Comparing Fluoride Varnish and Sealant to Prevent White Spots in Orthodontic Patients
|
N/A | |
| Completed |
NCT02027922 -
Clinical Effectiveness of Various Professionally Applied Fluoride Prophylaxes in Groups at High Risk
|
N/A | |
| Completed |
NCT04908293 -
Home Remineralization of White Spot Lesions With Two Different Toothpastes.
|
N/A | |
| Not yet recruiting |
NCT05868603 -
Effect of Different Remineralization Gels
|
N/A | |
| Not yet recruiting |
NCT06331442 -
The Effect of Photodynamic Therapy on Plaque in Orthodontic Patients
|
N/A | |
| Not yet recruiting |
NCT05306691 -
Remineralizing Efficacy of Giomer Varnish vs. Fluoride Varnish in Management of White Spot Lesions in Adult Patients
|
Early Phase 1 | |
| Active, not recruiting |
NCT06166849 -
Clinical Evaluation of an Experimental Remineralization Product
|
N/A | |
| Completed |
NCT05775250 -
Evaluation of Two Varnishes on the Improvement of White Spot Lesions in Children
|
N/A | |
| Completed |
NCT03114475 -
Effect of CO2 Laser on Enamel White Spot Lesion Formation Around Orthodontic Brackets
|
N/A | |
| Active, not recruiting |
NCT06403371 -
The Effect of Fluoride Varnish on White Spot Lesion in Clear Aligner Orthodontic Patients
|
N/A | |
| Completed |
NCT05771077 -
Effect of Poly Amido Amine Dendrimer, Nano-hydroxyapatite
|
Phase 1 | |
| Completed |
NCT05721586 -
Self-assembling Peptide With Sodium Fluoride in Treating White Spot Lesionss in Primary Teeth
|
N/A |