White Spot Lesion of Tooth Clinical Trial
Official title:
The Color Masking Potentials of a Bioactive Glass Adhesive and the Resin ICON on the White Spot Lesions. A Comparative Clinical Trial
The non cavitated white-spot lesion (WSL) occurs after sometime during fixed orthodontic treatments, and their treatment is mandatory before going into frank cavitation. The resin infiltration material (ICON, DMG, America) is considered to be the gold standard resin infiltrationmaterial used for WSL treatment. It is an efficient material in arresting WSLs and has high favorable esthetic recovery. Furthermore, biomaterials like bioactive glass adhesives HI-bond universal adhesive have always been used for replacement, repair and generation of dental hard tissues. The hypotheses of this study are: 1. There will be no differences in color masking effect on WSLs managed by bioactive glass adhesive or ICON resin infiltration. 2. There will be no significant addition of mineral content into WSLs after treating it with bioactive glass adhesive HI-Bond universal or with ICON.
After sample size calculations were carried out a total sample size of 150 teeth will be included (75 teeth will be treated with ICON; and 75 other teeth will be treated with HI-Bond universal]. Split mouth study design involves treating WSLs in two different quadrants in each participant. Treatments will be done according to manufacturer's instruction. The WSLs in the teeth of one quadrant will receive treatments with the ICON (DMG, America) , and the others in the opposite quadrant will receive treatments with the bioactive glass adhesive HI-Bond universal (MEDICLUS, south Korea). Before receiving the treatment, the WSLs will be tested at baseline by Quantitative light-induced fluorescence (QLF) device then the test will be repeated at 1-month after the treatment for the quadrant that received bioactive glass adhesive. ;
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Completed |
NCT03004196 -
Comparison of Efficacy Of Probiotic Toothpaste and Chlorhexidine Mouthwash To Reduce S.Mutans
|
Phase 1/Phase 2 | |
| Terminated |
NCT04827966 -
Remineralization Agents for the Treatment of White Spot Lesions
|
N/A | |
| Not yet recruiting |
NCT03973554 -
Caries Prevention Potential of Pearl Powder Versus CPP-ACP on Enamel White Spot Lesions
|
Phase 2 | |
| Completed |
NCT05757440 -
Effect of Low-viscosity Resin Infiltration on Color Change of Enamel White Spot Lesions
|
N/A | |
| Completed |
NCT05871619 -
Combined Application of Diode Laser and Different Remineralizing Agents on White Spot Lesions
|
N/A | |
| Not yet recruiting |
NCT03930927 -
Effect of Self Assembling Peptide on White Spot Lesion
|
Early Phase 1 | |
| Not yet recruiting |
NCT03721198 -
RMGI Varnish Versus APF Gel in Prevention of White Spot Lesions During Orthodontic Treatment
|
N/A | |
| Completed |
NCT03526276 -
Effect of Different Pastes on Remineralization of Early Caries Lesions in Primary Teeth
|
N/A | |
| Recruiting |
NCT03823612 -
Reminerlization Potential of Innovative Biomimetic Material in Caries White Spot Lesions
|
Phase 4 | |
| Recruiting |
NCT05206539 -
Efficacy of Different Agents in Treatment of Initial Caries on Smooth Surfaces in Permanent Teeth in Children
|
Phase 3 | |
| Completed |
NCT04401280 -
Bioactive Glass in the Treatment of Enamel White Spot Lesions
|
Phase 3 | |
| Completed |
NCT03738839 -
A Comparative Assessment of Orthodontic Treatment Outcomes Using the Quantitative Light-Induced Fluorescence Method
|
N/A | |
| Recruiting |
NCT04994314 -
White Spot Lesions Prevention During Orthodontic Fixed Appliance Treatment: a Randomized Clinical Trial
|
Phase 3 | |
| Completed |
NCT04992481 -
Fluoride Varnish, Ozone, Octenidin and WSLs in Orthodontic Patients
|
N/A | |
| Active, not recruiting |
NCT05764187 -
Incidence of White Spot Lesions Around Ceramic Brackets Compared With Metal Brackets
|
N/A | |
| Recruiting |
NCT03217084 -
Treatment of Postorthodontic White Spot Lesions
|
Phase 4 |