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White Spot Lesion of Tooth clinical trials

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NCT ID: NCT06402500 Recruiting - Clinical trials for White Spot Lesion of Tooth

Color Masking Potential of Bioactive and ICON Materials

Start date: December 1, 2023
Phase: N/A
Study type: Interventional

The non cavitated white-spot lesion (WSL) occurs after sometime during fixed orthodontic treatments, and their treatment is mandatory before going into frank cavitation. The resin infiltration material (ICON, DMG, America) is considered to be the gold standard resin infiltrationmaterial used for WSL treatment. It is an efficient material in arresting WSLs and has high favorable esthetic recovery. Furthermore, biomaterials like bioactive glass adhesives HI-bond universal adhesive have always been used for replacement, repair and generation of dental hard tissues. The hypotheses of this study are: 1. There will be no differences in color masking effect on WSLs managed by bioactive glass adhesive or ICON resin infiltration. 2. There will be no significant addition of mineral content into WSLs after treating it with bioactive glass adhesive HI-Bond universal or with ICON.

NCT ID: NCT05871619 Completed - Clinical trials for White Spot Lesion of Tooth

Combined Application of Diode Laser and Different Remineralizing Agents on White Spot Lesions

Whitespot
Start date: May 5, 2022
Phase: N/A
Study type: Interventional

Dental caries is a very common condition, and although it has become less common, it still represents a serious public health risk. Caries symptoms range from the earliest molecular alterations in the tooth's apatite crystals to an apparent white spot lesion (WSL) or eventual cavitation. The white spot lesion looks chalky because minerals are being lost from both the surface and the underside of the enamel. A relatively simple and noninvasive caries preventive regimen in treating white spot lesions with low-level laser irradiation, either alone or with topical fluoride treatment. This treatment results in reduced enamel solubility and dissolution.

NCT ID: NCT05764187 Active, not recruiting - Clinical trials for White Spot Lesion of Tooth

Incidence of White Spot Lesions Around Ceramic Brackets Compared With Metal Brackets

Start date: December 28, 2021
Phase: N/A
Study type: Interventional

The main objective of this study was to investigate the relation between ceramic brackets and the development of white spot lesions (WSLs) compared to that associated with conventional metal brackets.

NCT ID: NCT05757440 Completed - Clinical trials for White Spot Lesion of Tooth

Effect of Low-viscosity Resin Infiltration on Color Change of Enamel White Spot Lesions

Start date: November 20, 2020
Phase: N/A
Study type: Interventional

this study aimed to assess the effect of the application of the low-viscosity Icon resin infiltrate on the color change of the diagnosed white spot enamel lesions (WSLs) over 3-, 6-, and 12-m follow-up periods. The ICDAS scoring system was used to visually diagnose WSLs in a total of 96 anterior teeth in 49 participants and the teeth were then were evaluated for their color change using a spectrophotometer. According to the manufacturer directions the Icon kit was applied to the WSLs-diagnosed teeth as follows: the WSLs were treated with 15% hydrofluoric acid (Icon-Etch) was applied to the lesions for 120 seconds then it was rinsed for 30 seconds. Next, the etched WSLs were treated with 99% ethanol (Icon-dry) and for 30 seconds. Then the Icon-Resin was applied and light cured for 40 seconds. The change of color was done after 3-, 6- and 12-month . The mean and standard deviation values were statistically analyzed with the repeated measure ANOVA test and the Paired sample t-test.

NCT ID: NCT05206539 Recruiting - Clinical trials for White Spot Lesion of Tooth

Efficacy of Different Agents in Treatment of Initial Caries on Smooth Surfaces in Permanent Teeth in Children

Start date: June 1, 2024
Phase: Phase 3
Study type: Interventional

White spot lesions (WSL) are characterized by an apparently intact outer surface and a demineralized subsurface, and are considered the first clinical sign of dental caries. Aim of this study is to determine the treatment potential of self-assembling peptide (P11-4), casein phosphopeptide-amorphos calcium fluoride phosphate (CPP-ACFP) and resin infiltration technique to reverse or arrest the WSLs in the same oral environments in pediatric patients using visual assessments and laser fluorescence investigation.

NCT ID: NCT04994314 Recruiting - Clinical trials for White Spot Lesion of Tooth

White Spot Lesions Prevention During Orthodontic Fixed Appliance Treatment: a Randomized Clinical Trial

Start date: February 15, 2021
Phase: Phase 3
Study type: Interventional

The aim of this study is to evaluate the effectiveness of calcium fluoride nanoparticles containing orthodontic primer in preventing or decreasing the incidence WSLs over a period of 6 months in patients with fixed orthodontic appliances. This study proposed to be double blinded, split mouth, randomized clinical trial, with equal randomization (1:1 allocation ratio).

NCT ID: NCT04992481 Completed - Clinical trials for White Spot Lesion of Tooth

Fluoride Varnish, Ozone, Octenidin and WSLs in Orthodontic Patients

Start date: February 1, 2013
Phase: N/A
Study type: Interventional

Objectives: to assess the efficiency of four prophylactic protocols on white spot lesions during orthodontic treatment: 1. professional mechanical tooth cleaning (PMTC)+fluoride varnish, 2. PMTC+fluoride varnish+gaseous ozone therapy 3. PMTC+fluoride varnish+domestic octenidin mouth rinse, 4. PMTC+fluoride varnish+domestic octenidin mouth rinse+ gaseous ozone therapy versus a control group not subjected to any prophylactic program. Materials and Methods: Patients (n=150, 111 women and 39 men, age 16-50y,) who began orthodontic treatment with fixed appliances bonded to both dental arches have been provided with detailed initial oral hygiene instruction recommendations. The hygienic recommendations comprised: toothbrushing every surface after every meal (4 minutes) with a fluoridated toothpaste (1450 ppm) using the roll and Bass methods with a soft toothbrush recommended for fixed appliance, interdental toothbrushes, single-tufted brushes and dental floss recommended for fixed appliance. An instruction leaflet has been delivered to every subject, as well. A reinstruction was made during every control visit referring to the results of the oral hygiene assessment. Subsequently, the patients were randomly allocated (using number random generator) into five groups (n=30), including four study groups (I, II, III, IV) and one control group (K). Group I: professional mechanical tooth cleaning (PMTC)+fluoride varnish, group II: PMTC+fluoride varnish+gaseous ozone therapy, group III: PMTC+fluoride varnish+domestic octenidin mouth rinse, group IV: PMTC+fluoride varnish+domestic octenidin mouth rinse+ gaseous ozone therapy, control group (K) not subjected to any prophylactic program. The period of observation was 12 months, with prophylactic visits every four weeks and examinations every 12 weeks. The assessment of white spot lesions was proceeded on the labial surfaces of upper and lower teeth, with patient on the dental chair in proper dental lighting, after cleaning and drying the assessed surfaces.

NCT ID: NCT04827966 Terminated - Clinical trials for White Spot Lesion of Tooth

Remineralization Agents for the Treatment of White Spot Lesions

Start date: September 1, 2022
Phase: N/A
Study type: Interventional

Clinically, formation of white spots can occur as early as 4 weeks into orthodontic treatment and very common in high caries risk individuals. When left untreated, the calcium loss continues, the enamel breaks down entirely, and a cavity appears. These can cause caries thereby leading to poor esthetics and patient dissatisfaction. The labio-gingival area of the lateral incisors is the most common site for WSL and the maxillary posterior segments are the least common site, with males affected more in comparison with females.Hence inducing remineralization of existing lesions is the key treatment to prevent cavitation.

NCT ID: NCT04401280 Completed - Clinical trials for White Spot Lesion of Tooth

Bioactive Glass in the Treatment of Enamel White Spot Lesions

Start date: June 1, 2020
Phase: Phase 3
Study type: Interventional

the aim of this study is to evaluate the effectiveness of BiominF® and Novamin® in comparison to Casein phosphopeptide-amorphous calcium phosphate (CPP-ACP) in the treatment of enamel white spot lesions

NCT ID: NCT03973554 Not yet recruiting - Clinical trials for White Spot Lesion of Tooth

Caries Prevention Potential of Pearl Powder Versus CPP-ACP on Enamel White Spot Lesions

Start date: October 30, 2019
Phase: Phase 2
Study type: Interventional

to evaluate the caries prevention potential of pearl powder against CPP-ACP in enamel white spot lesions.