Migraine Disorders Clinical Trial
Official title:
The Relationship Between Right-to-left Shunt and Brain White Matter Lesions in Chinese Patients With Migraine:a Multicenter Study. CAMBRAIN Study.
The purpose of the study is to evaluate the prevalence of white matter lesions in Chinese migraineurs with and without right-to-left shunt. The aim is to study the relationship among right-to-left shunt, migraine and white matter lesions.
This is a prospective multicenter study of Chinese population. Participants (normal
individuals without migraine and migraineurs) are included after standardized diagnostic
procedures (TCD and migraine diagnosis). For all the participants, brain MRI and c-TCD are
required. Up to 10-15 study sites nationwide will be needed to recruit the planned
participant population during a 1-year period.
The information of each participants will be registered, including basic facts, the
longitudinal headache history, frequency, location, quality, intensity, duration, accompanied
symptoms, precipitating and exacerbating factors, with or without aura, and Headache Impact
Test-6 (HIT-6) questionnaire.
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