Whiplash Injuries Clinical Trial
Official title:
Shifting Away From Pain: Neurocognitive Approach to Explain and Predict the Response to the Modern Neuroscience Approach for Treating Patients With Whiplash Associated Disorders
The broad aim of this study is to investigate the effect of a modern neuroscience approach, which combines education on pain neuroscience with cognition-targeted exercise therapy and stress management, on brain structure and networks in patients with chronic whiplash-associated disorders (CWAD) in comparison to a control physiotherapy treatment.
This project runs in parallel to a larger randomized-controlled trial (RCT) in which the 'modern neuroscience approach to WAD' is compared to usual care evidence-based physiotherapy (clinical trial registration number: NCT03239938). For the current study, additional magnetic resonance imaging (MRI) measures will be taken in a subsample of patients, who will be recruited from this larger RCT. In addition, a pain-free age- and sex-matched control group will be recruited for comparison. The current study consists of 2 MRI measurements that will take place at the University Hospital of Ghent (UZ Gent): baseline (pre-treatment) and follow-up (post-treatment; approximately 16 weeks after baseline). After pre-treatment assessment, the patients will be randomly allocated to the modern neuroscience approach or usual care physiotherapy, as part of the RCT. ;
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Terminated |
NCT00952510 -
Maastricht Neck Study: Cervical Range of Motion in Whiplash Patients
|
N/A | |
| Completed |
NCT03664934 -
Pathophysiological Mechanism Behind Prolonged Whiplash Associated Disorders
|
N/A | |
| Withdrawn |
NCT02060734 -
Lidocaine Injection Versus Sham Needling in Treating Whiplash Associated Disorder
|
Phase 4 | |
| Completed |
NCT01957033 -
Responses of People With Neck Pain Being Treated With Varying Doses of Manual Therapy: A Pilot Study
|
N/A | |
| Completed |
NCT01699334 -
Effectiveness of an Educational Video Following Acute Whiplash Trauma
|
N/A | |
| Not yet recruiting |
NCT05536570 -
Whiplash-induced Thoracic Outlet Syndrome Treated With Botulinum Toxin.
|
Phase 4 | |
| Completed |
NCT04167930 -
The Analysis for Termination of Treatment and Satisfaction in Traffic Accident Patient
|
||
| Completed |
NCT03502928 -
Efficacy of the Use of Dry Needling in Conventional Non-invasive Treatment of Acute and Subacute Whiplash
|
N/A | |
| Completed |
NCT03729856 -
A Novel Intervention to Promote Engagement in Physical Activity for Individuals With Whiplash Associated Disorder
|
N/A | |
| Completed |
NCT00021476 -
Preventing Chronic Whiplash Pain
|
Phase 3 | |
| Completed |
NCT03949959 -
Effectiveness of Physiotherapy Following PRP for Chronic Whiplash
|
N/A | |
| Recruiting |
NCT05198258 -
Implementation and Evaluation of Neck-specific Exercises
|
N/A | |
| Not yet recruiting |
NCT01369238 -
East-West Collaborative Medicine Using Bee-Venom Acupuncture on Whiplash-Associated Disorders
|
N/A | |
| Completed |
NCT02625896 -
Free Fall Acrobatics to Reduce Neck Loads During Parachute Opening Shock: Evaluation of an Intervention.
|
N/A | |
| Recruiting |
NCT04940923 -
Neuroinflammation as a Predictor of Chronicity in Whiplash
|
||
| Terminated |
NCT05161767 -
Shifting Away From Pain: Neurocognitive Approach to Explain and Predict Recovery Following Whiplash Injury
|
||
| Recruiting |
NCT06386068 -
Interdisciplinary Value-based Cognitive Behavioral Treatment for People With Persistent Whiplash Associated Disorders.
|
N/A | |
| Completed |
NCT02692937 -
Is Chronic Whiplash-associated Pain of Neurogenic Origin?
|
N/A | |
| Completed |
NCT05041985 -
Clinical Efficacy of Diazepam After Whiplash : A Randomized Controlled Study
|
Phase 4 | |
| Completed |
NCT01601912 -
Unraveling the Nature of Impaired Pain Inhibition in Patients With Chronic Whiplash-associated Disorders
|
Phase 4 |