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Warts clinical trials

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NCT ID: NCT05712811 Completed - Warts Clinical Trials

Comparison of Cryotherapy and Peeling Agent in the Treatment of Common Warts

Start date: June 1, 2022
Phase: N/A
Study type: Interventional

Objective: To compare the efficacy of cryotherapy using liquid nitrogen (cryoget method) versus trichloroacetic acid 90% (applicator method) in treatment of common warts. Study Design: Randomized Control Trial. Place And Duration of Study: Department of Dermatology, CMH Abbottabad from Jun 2022 to Nov, 2022.

NCT ID: NCT05652998 Active, not recruiting - Plane Wart Clinical Trials

Comparison Between Intralesional Injection of Plasma Rich Platelets and Candida Antigen in Plane Warts

Start date: October 15, 2021
Phase: Phase 4
Study type: Interventional

To compare the efficacy of intralesional injection of autologous plasma rich platelets and candida antigen in treatment of patients with plane warts .

NCT ID: NCT05625633 Recruiting - Warts Clinical Trials

Human Papillomavirus (HPV) Vaccination vs. Placebo for the Treatment of Refractory Cutaneous Warts

Start date: March 25, 2024
Phase: Phase 2/Phase 3
Study type: Interventional

This double-blinded clinical trial randomly assigns participants with refractory cutaneous warts to receive either treatment with the human papillomavirus (HPV) vaccine or a placebo to assess the efficacy of HPV vaccination for the treatment of refractory cutaneous warts.

NCT ID: NCT05622916 Not yet recruiting - Anogenital Wart Clinical Trials

Topical Ethanol Extract (Piper Crocatum) for Anogenital Warts

Start date: November 30, 2022
Phase: N/A
Study type: Interventional

This clinical trial aims to assess the efficacy of topical Piper crocatum in treating Anogenital warts. It aims to answer - the clinical efficacy of treating anogenital warts - the expression of Foxp3+ regulatory T (Treg), TGF/Tumor Growth Factor -β1, and IFN/interferon -γ of anogenital wart lesion Participants will be allocated into two topical treatments, intervention and active comparator Trichloroacetic Acid (TCA) 90%. The researchers assume that intervention is superior compared to TCA 90%

NCT ID: NCT05617950 Not yet recruiting - Warts Clinical Trials

Salicylic Acid Versus Cryotherapy for the Treatment of HPV1-induced Plantar Warts

Start date: November 2022
Phase: N/A
Study type: Interventional

To evaluate whether salicylic acid was superior to cryotherapy for plantar warts

NCT ID: NCT05616078 Not yet recruiting - Warts Clinical Trials

Laser Versus Cryotherapy for the Treatment of Recalcitrant Warts

Start date: November 2022
Phase: N/A
Study type: Interventional

To evaluate whether laser was superior to cryotherapy for recalcitrant warts

NCT ID: NCT05599971 Not yet recruiting - Plantar Wart Clinical Trials

Intralesional Injection of Combined Digoxin and Furosemide Versus 5-Flurouracil in Plantar Warts

Start date: February 22, 2023
Phase: N/A
Study type: Interventional

The aim of the current work is to evaluate the efficacy and safety of intralesional combined Digoxin and furosemide versus intralesional 5-flurouracil in the treatment of plantar warts.

NCT ID: NCT05592041 Completed - Plantar Wart Clinical Trials

Studying of Natural Constituents' Treatment of Plantar Warts

Start date: October 20, 2022
Phase: Early Phase 1
Study type: Interventional

Moringa banana nigella and Banna coat extract were prepared and formulated in the form of bi gel for transdermal delivery of these plant extracts. The formulation was prepared and charterized for organoleptic charters, morphology, and penetration efficacy. The optimised formulation was assessed clinically on patients suffering from plantar warts. The clinical study was phase 1 and interventional randomised allocation.

NCT ID: NCT05588999 Completed - Plantar Wart Clinical Trials

Comparative Study Between Treatment With Cryotherapy Alone Versus Cryotherapy Plus Salicylic Acid Dressing for Planter Warts

Start date: March 1, 2022
Phase: Phase 1
Study type: Interventional

Verrucae plantaris (plantar warts) are a frequent cutaneous lesion of the plantar portion of the foot caused by the human papillomavirus (HPV) (HPV).Although HPV is ubiquitous in our environment, cellular and humoral immune responses typically prevent it from spreading or eliminate it. Warts can be painful and can lead to other difficulties, but there are some populations that are at a higher risk of getting HPV because they encounter the virus more frequently. In addition to infecting other people, HPV can also spread to other locations in the area. While reducing exposure to risk factors can help prevent plantar wart infection, HPV's widespread nature makes it difficult for such efforts to be effective. It has been shown in research that plantar warts can spread from person to person through just physical contact with the sores. Warts are more common in people with HPV because the virus disrupts the epithelial barrier. There are over a hundred different forms of the HPV virus, so even though some warts go away on their own after a few years, others may need medical attention. Warts, according to a number of studies, are extremely common (affecting around 10% of the population) all over the world. More cases of HPV infection have been observed among people under the age of 30, compared to those beyond the age of 30. The estimated prevalence in the United States is between 10% and 20%. However, people with compromised immune systems and those who work with meat are disproportionately at risk. The cancerous transformation of warts is quite rare. Even while verrucous carcinoma, a malignant form of wart development, is possible, it seldom spreads and only causes localised tissue loss. Plantar warts are treated in a manner that takes into account the patient's symptoms, personal preferences, and financial situation. Even though there are several therapy options, none of them are particularly effective, and relapses are common after any treatment. As a result, the most accessible and least distressing treatment option should be prioritised. Since salicylic acid can be used by the patient at home and does not require a doctor's prescription, it is often regarded a first-line therapy for the common wart. It can be as high as 70% effective in curing the disease. Other effective therapies for plantar warts include cryotherapy, retinoic acid, podophyllin, topical 5-fluorouracil, interferon, and imiquimod. Salicylic acid, in conjunction with cryotherapy, has shown therapeutic efficacy in patients with only foot warts, according to a single prior study. Patients who were given cryotherapy in this trial had a 58% success rate at recovery, whereas those given salicylic acid had a 41% success rate. Hover, there is no discernible statistical difference. The purpose of this study was to compare the effectiveness of cryotherapy alone against cryotherapy plus salicylic acid dressing for planter warts, keeping in mind the prevalence of treatment for plantar warts and the lack of a well-established, practically applicable, and reliably preventative method in our local population.

NCT ID: NCT05520658 Recruiting - Plantar Wart Clinical Trials

Evaluation of the Efficacy of Intralesional Injection of Combined Digoxin and Furosemide Versus 5 - Fluorouracil in Treatment of Plantar Warts

Start date: July 1, 2022
Phase: N/A
Study type: Interventional

Warts are common skin infections caused by human papillomavirus (HPV), which can cause a variety of skin presentations according to its type, site and the immune status .Nongenital warts may be presented as common, plane, plantar, filiform, or mucosal warts .Most people are affected by cutaneous warts, either plantar warts or common warts .prevalence of skin warts is between 3% and 13% and plantar warts are about 30% of skin warts in western world .Majority of cases occur in adolescent and young adults