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Warts clinical trials

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NCT ID: NCT06261684 Recruiting - Plantar Wart Clinical Trials

Intralesional Acyclovir Versus Cryotherapy in the Treatment of Plantar Warts. A Randomized Controlled Trial.

Start date: October 1, 2023
Phase: Phase 2/Phase 3
Study type: Interventional

The goal of this prospective randomized controlled study is to study the safety and efficacy of intralesional acyclovir compared to cryotherapy in plantar warts. The main questions needed to be answered are: 1. Is Intralesional acyclovir safe for plantar warts? 2. Is Intralesional acyclovir more efficient in treating plantar warts compared to cryotherapy?

NCT ID: NCT06214559 Recruiting - Warts Clinical Trials

Evaluate the Effectiveness and the Safety of a Medical Device in the Treatment of Common Warts and Plantar Warts.

Start date: February 19, 2024
Phase: N/A
Study type: Interventional

The principal aim of this study is to evaluate the efficacy and the safety of the tested product on common and plantar wart after 35 days of treatment. For this study, 33 patients presenting at least one common wart on the fingers, back on the hand or a plantar wart of a size between 0.1 and 0.5cm and present since less than 6 months will be included to reach this objective

NCT ID: NCT05937672 Recruiting - Clinical trials for Molluscum Contagiosum

Cold Atmospheric Plasma Device Extension Study

Start date: September 18, 2023
Phase: Phase 3
Study type: Interventional

Patients between 4-21 years of age with at least one wart or molluscum lesion are eligible to participate in this study. The duration of the study is a minimum of 4 weeks with the maximum duration of monthly treatments for one year, depending on lesion clearance. The number of lesions will be chosen by the dermatologist. Patients who opt to participate will receive non-thermal, or cold, atmospheric plasma to treat all lesions selected. Safety profile as well as changes in size, pain and appearance will be measured. Photographs and dermatologist impressions will be used to measure treatment response.

NCT ID: NCT05889845 Recruiting - Clinical trials for Common Warts (Verruca Vulgaris)

Candin for the Treatment of Common Warts

Start date: March 5, 2024
Phase: Phase 3
Study type: Interventional

The goal of this clinical trial is to compare outcome in healthy subjects 12 years of age and older with at least 3, but no more than 20, common warts (Verruca vulgaris) following treatment with Candin or placebo. The main questions it aims to answer are: - does treatment with Candin result in better clearance of warts than placebo - how many injections are required to result in wart clearance Participants will - have one wart selected for injection every two weeks until clearance - return 12 weeks after wart clearance for assessment of durability of response

NCT ID: NCT05799157 Recruiting - Warts Clinical Trials

Safety and Efficacy of VDMN-21 Patch in Subjects With Common Warts

Start date: February 28, 2023
Phase: Phase 2
Study type: Interventional

This Phase 2 study has been designed to determine the safety and efficacy of repeated treatment sessions of VDMN-21 patch at two dose strengths as compared to a matched vehicle control patch in subjects with verruca vulgaris

NCT ID: NCT05761002 Recruiting - Clinical trials for Human Papilloma Virus

Human Papilloma Virus Genotypes and Treatment Outcomes of Intralesional Immunotherapy of Anogenital Warts

Start date: June 1, 2022
Phase: N/A
Study type: Interventional

This study aims to investigate the relationship between HPV genotypes and treatment outcomes of intralesional immunotherapy of anogenital warts with the quadrivalent vaccine (Gardasil).

NCT ID: NCT05625633 Recruiting - Warts Clinical Trials

Human Papillomavirus (HPV) Vaccination vs. Placebo for the Treatment of Refractory Cutaneous Warts

Start date: March 25, 2024
Phase: Phase 2/Phase 3
Study type: Interventional

This double-blinded clinical trial randomly assigns participants with refractory cutaneous warts to receive either treatment with the human papillomavirus (HPV) vaccine or a placebo to assess the efficacy of HPV vaccination for the treatment of refractory cutaneous warts.

NCT ID: NCT05520658 Recruiting - Plantar Wart Clinical Trials

Evaluation of the Efficacy of Intralesional Injection of Combined Digoxin and Furosemide Versus 5 - Fluorouracil in Treatment of Plantar Warts

Start date: July 1, 2022
Phase: N/A
Study type: Interventional

Warts are common skin infections caused by human papillomavirus (HPV), which can cause a variety of skin presentations according to its type, site and the immune status .Nongenital warts may be presented as common, plane, plantar, filiform, or mucosal warts .Most people are affected by cutaneous warts, either plantar warts or common warts .prevalence of skin warts is between 3% and 13% and plantar warts are about 30% of skin warts in western world .Majority of cases occur in adolescent and young adults

NCT ID: NCT05488860 Recruiting - Skin Diseases Clinical Trials

Piezoelectric Drived Microneedling in Treating Refractory Skin Diseases

Start date: July 30, 2022
Phase: N/A
Study type: Interventional

Piezoelectric drived microneedling treats refractory skin disorders using hollow microneedles assisted by ultrasound. Mechanically, the injection of medicine by hollow microneedling could makes the distribution of medicine more evenly. And the addition of ultrasound technique improves the effectiveness of microneedling. Investigators plan to conduct a pilot study to investigate the efficacy of using piezoelectric drived microneedles in treating refractory skin diseases.

NCT ID: NCT05429151 Recruiting - Clinical trials for Acyclovir and Candida Antigen in Treatment of Plantar Wart

Intralesional Injection of Acyclovir Versus Candida Antigen in Treatment of Plantar Warts

Start date: June 13, 2022
Phase: Phase 4
Study type: Interventional

This study aims to evaluate the efficacy of intralesional injection of acyclovir versus candida antigen in plantar wart patients will be randomly divided into 2 groups,At least 20 patients will be enrolled in each group. Group 1: will be treated with intralesional injection of acyclovir 250 mg acyclovir vial diluted with 3.5 ml saline to get approximately 70 mg/ml solution. The base of each wart was injected with 0.1 ml of intralesional acyclovir (70 mg/ml) every 2 weeks until the resolution of warts or for a maximum of 5 sessions Group 2: will be treated by intralesional Candida antigen injection (candida antigen ) at a dose of 0.2 mL. injected into the largest wart every 2 weeks until complete clearance of warts or for a maximum of 5 treatment sessions. 3.Patient evaluation: Assessment of treatment efficacy and side effects will be carried out by clinical examination and comparative photographic evaluation and dermoscopy