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Vomiting clinical trials

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NCT ID: NCT00701909 Completed - Nausea Clinical Trials

Pain Medicine for Wound Care Procedures

Start date: June 2008
Phase: Phase 3
Study type: Interventional

This is a randomized double-blind study to determine if the administration of a small-dose of ketamine (an anesthetic)added to morphine (an opioid) contributes to reducing pain intensity during open wound care procedure (WCP)in patients who have had a traumatic injury and are in an Intensive Care Unit. Patients will be randomized to receive morphine plus saline (a placebo) or morphine plus ketamine before the WCP. The second time the patient is scheduled for WCP (no less than 24 hours), patients will be crossed over to receive the treatment they did not receive the first time. It is hypothesized that patients who receive the combination of morphine and ketamine will have better pain control during the procedure than patients who just receive morphine.

NCT ID: NCT00696280 Completed - Vomiting Clinical Trials

Observational Study of Delayed Nausea and Vomiting

DelayedNaus
Start date: November 2006
Phase: N/A
Study type: Observational

Delayed emesis following administration of carboplatin-based chemotherapy despite prophylaxis with standard antiemetic prophylaxis (5-HT3 and corticosteroid) remains a clinically significant and distressing problem for patients with cancer. The incidence of delayed emesis appears to be higher in women compared to men.

NCT ID: NCT00687011 Completed - Neoplasms Clinical Trials

Palonosetron Plus Dexamethasone in Moderately Emetogenic Chemotherapy Induced Nausea and Vomiting (Study P04594)

Start date: October 10, 2006
Phase: Phase 4
Study type: Interventional

The purpose of this study is to determine if a single intravenous (IV) dose of palonosetron 0.25 mg plus a single IV dose of dexamethasone 8 mg is effective to prevent nausea and vomiting induced by moderately emetogenic chemotherapy in subjects with cancer.

NCT ID: NCT00684463 Completed - Neoplasms Clinical Trials

Palonosetron in Moderately and Highly Emetogenic Chemotherapy Induced Nausea and Vomiting (Study P04935)(COMPLETED)

Start date: April 11, 2007
Phase: Phase 4
Study type: Interventional

The purpose of this study is to evaluate the efficacy and safety of single IV doses of Onicit® (Palonosetron) 0.25 mg in the prevention of acute and delayed nausea and vomiting associated with moderate and highly emetogenic chemotherapy.

NCT ID: NCT00666783 Completed - Clinical trials for Chemotherapy-Induced Nausea and Vomiting

An Efficacy and Safety Study of Palonosetron in Preventing Chemotherapy-Induced Nausea and Vomiting (CINV) in the Chinese Cancer Patients

Start date: n/a
Phase: Phase 2
Study type: Interventional

This clinical study was designed to demonstrate that a single, intravenous dose of palonosetron 0.25 mg was not inferior to granisetron 3 mg in preventing acute and delayed CINV and was also well tolerated in the Chinese cancer patients.

NCT ID: NCT00659737 Completed - Nausea Clinical Trials

Comparison of Oral Aprepitant and Transdermal Scopolamine for Preventing Postoperative Nausea and Vomiting

Start date: April 2008
Phase: N/A
Study type: Interventional

Recent evidence suggests multiple drug therapy is superior to single agents. The study compares the incidence of nausea, vomiting, need for rescue medication, prolonged PACU time, and unplanned hospital admission in patients with high risk for PONV treated with oral aprepitant with or without transdermal scopolamine preoperatively.

NCT ID: NCT00642512 Completed - Clinical trials for Chemotherapy Induced Nausea and Vomiting

Dronabinol Versus Standard Ondansetron Antiemetic Therapy in Preventing Delayed-Onset Chemotherapy-Induced Nausea and Vomiting

Start date: July 2003
Phase: Phase 3
Study type: Interventional

The primary purpose of the study is to determine the efficacy of oral dronabinol versus standard ondansetron antiemetic therapy in preventing delayed-onset chemotherapy-induced nausea and vomiting (CINV) or retching by measuring the incidence of total response of nausea and vomiting and/or retching following administration of moderate-to-high emetogenic chemotherapeutic agents.

NCT ID: NCT00642499 Completed - HIV Infections Clinical Trials

Dronabinol Versus Placebo in Treatment and Prevention of Highly Active Anti-Retroviral Therapy (HAART)-Related Nausea and Vomiting

Start date: August 2003
Phase: Phase 2
Study type: Interventional

The primary purpose of this study is to determine if dronabinol is effective in preventing or treating nausea caused by HAART (highly active anti-retroviral therapy) in HIV and AIDS patients

NCT ID: NCT00621660 Completed - Nausea Clinical Trials

Acupuncture Versus Sham for Radiotherapy-Induced Emesis

Start date: January 2004
Phase: N/A
Study type: Interventional

The aim of this study is to evaluate if acupuncture prevents or reduces nausea or vomiting during radiotherapy

NCT ID: NCT00619359 Completed - Clinical trials for Chemotherapy-Induced Nausea and Vomiting (CINV)

Evaluation of Fosaprepitant (MK0517) in Single Dose Schedule (0517-017)

EASE
Start date: February 2008
Phase: Phase 3
Study type: Interventional

The purpose of this study is to examine the safety, tolerability, and efficacy of MK0517 to prevent Chemotherapy-Induced Nausea and Vomiting (CINV) associated with Cisplatin chemotherapy.