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Vocal Cord Paralysis clinical trials

View clinical trials related to Vocal Cord Paralysis.

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NCT ID: NCT01824849 Completed - Airway Obstruction Clinical Trials

Total Versus Partial Arytenoidectomy in Bilateral Vocal Fold Paralysis

Start date: January 2011
Phase: N/A
Study type: Interventional

Total arytenoidectomy is claimed to increase risk of aspiration and cause more voice loss than other operations performed for bilateral vocal fold paralysis (BVFP). However, objective evidence for such conclusion is lacking. There is no study comparing swallowing and voice after total and partial arytenoidectomy.

NCT ID: NCT01690806 Completed - Clinical trials for Malignant Neoplasm of Thyroid

Dexamethasone for the Prevention of Recurrent Laryngeal Nerve Palsy

Start date: January 2008
Phase: N/A
Study type: Observational

Recurrent laryngeal nerve dysfunction and hypoparathyroidism are well-recognized important complications of thyroid surgery. The duration of convalescence, after non complicated thyroid operation, may depend on several factors of which pain and fatigue are the most important. Nausea and vomiting occur mainly on the day of operation. Glucocorticoids are well known for their analgesic, anti-inflammatory, immune modulating and antiemetic effects. The investigators therefore undertook the present study to investigate whether preoperative dexamethasone could improve surgical outcome in patients undergoing thyroid surgery.

NCT ID: NCT00845442 Completed - Clinical trials for Vocal Cord Paralysis

Dynamic Laryngeal Opening for Bilateral Vocal Fold Paralysis by an Implanted Stimulator

Start date: January 1, 2006
Phase: N/A
Study type: Interventional

People who had paralysis of the vocal cords are often prevented from breathing by this problem because the cords will not open, and the patients have to wear a tracheostomy (neck breathing tube) to bypass this airway obstruction. This study examines the effects of vocal cord opening triggered by a pacemaker implanted over the chest wall. The device is connected to a nerve taken from a muscle close to the larynx (voice box) and implanted into the paralysed laryngeal muscle so it can reinnervate it. When this process is complete after a few weeks, the stimulator is turned on and the level of vocal cord opening is assessed. Airway improvement is checked by pulmonary function tests and measurements of vocal cord opening. The ultimate goal of the study is to lead to situations where patients with bilateral vocal fold paralyses could get rid of the neck breathing tube to have less complications, be more comfortable and socially acceptable.

NCT ID: NCT00597844 Completed - Clinical trials for Unilateral Vocal Cord Paralysis

Improving Functional Outcomes in Patients With Unilateral Vocal Cord Paralysis: Assessment of Adaptation Using Functional Magnetic Resonance Imaging

Start date: July 2005
Phase: N/A
Study type: Interventional

The purpose of this study is to see how the brain re-learns to control the larynx in speaking and swallowing when undergoing surgical rehabilitation in the form of either thyroplasty or vocal fold augmentation for unilateral vocal cord paralysis. What is needed is information on how the brain re-learns to control speaking and swallowing so that we can eventually learn how to help patients re-learn faster after their procedure. Functional Magnetic Resonance Imaging (or fMRI) will allow us to image your brain as you speak and swallow. We will produce "brain maps" for speaking, swallowing and hand movements.

NCT ID: NCT00506103 Completed - Hemorrhage Clinical Trials

The No-Tie Technique Using the Harmonic Scalpel in Total Thyroidectomy With Central Neck Dissection: A Prospective Randomized Study

Start date: October 2006
Phase: N/A
Study type: Observational

To investigate the safety and efficacy of the no-tie technique using the harmonic scalpel (HS) in terms of the operating time and complications in total thyroidectomy with central neck dissection (CND). Recently, the HS has been used as an alternative to conventional hand-tied ligation for hemostasis in thyroid surgery, which is a time-consuming procedure. Very limited data have been published on evidence of its safety in total thyroidectomy accompanied by CND without supplementary hand-tied ligation.

NCT ID: NCT00382369 Completed - Clinical trials for Vocal Cord Paralysis

Whole Genome Scan of Extended Families With Familial Vocal Cord Paralysis

Start date: June 1, 2008
Phase: N/A
Study type: Observational

Vocal cord paralysis is a common cause of congenital stridor and airway obstruction. In this study we plan to identify the genetic locus of the genes in two extended families who suffer of the disease.

NCT ID: NCT00213616 Completed - Clinical trials for Vocal Cord Paralysis

Bilateral Laryngeal Paralysis Reinnervation

Start date: March 2004
Phase: N/A
Study type: Interventional

Bilateral laryngeal reinnervation induces a rise in laryngeal resistance and speech alteration. The aim of this study is to propose laryngeal reinnervation by a phrenic nerve root to patients with bilateral laryngeal paralysis.