Evaluation of Thriving, Substance Use, Mental Health, and Repeat Injury Among Participants in the THRIVE Program

Violence Clinical Trial

Official title:

Evaluation of Thriving, Substance Use, Mental Health and Repeat Injury Among Participants in the THRIVE Program

Clinical Trial Details — Status: Not yet recruiting

Administrative data

• NCT number: NCT06455943
• Other study ID #: THRIVE001
• Status: Not yet recruiting
• Start date: July 1, 2024
• Est. completion date: July 1, 2035

Study information

• Verified date: June 2024
• Source: Unity Health Toronto
• Contact: Jennifer Dekker, MSc
• Phone: 437-331-8644
• Email: jennifer.dekker[@]unityhealth.to
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

The goal of this observational study is to determine the impact of a hospital-based violence intervention program on a person's capacity to thrive and recurrent intentional injury. The aims of this study are:

1. To evaluate the impact of the HVIP on building personal capacity of youth who have experienced non-fatal violent injuries to thrive using:

• Established measure changes in positive psychology and clinical metrics

• A qualitative interview using thematic content analysis

2. Plot the methodology proposed to measure the impact of THRIVE on subsequent injuries using administrative data sources

Participants will complete surveys, participate in a semi-structured interview, and have their rate of recurrent intentional injury tracked over time.

Researchers will compare the rates of intentional reinjury between participants in the THRIVE program and those who present at other hospitals with similar injuries to see if there is a difference in the rate of recurrent intentional injury a 1, 5, and 10 years.

Recruitment information / eligibility

• Status: Not yet recruiting
• Enrollment: 90
• Est. completion date: July 1, 2035
• Est. primary completion date: July 1, 2026
• Accepts healthy volunteers: No
• Gender: All
• Age group: 14 Years to 29 Years

Eligibility

Inclusion Criteria:

• ages 14-29

• presentation with an injury due to violence (defined as a gun shot wound, stab wound, blunt or bodily force, inflicted by someone else)

• participant in the THRIVE Program

Exclusion Criteria:

• unable to consent due to language barrier or brain injury

• sexual assault

• child abuse

• self-inflicted injury

• residence >1 hour from Toronto city limits

Related Conditions & MeSH terms

• Assault
• Substance-Related Disorders
• Violence

Locations

Country	Name	City	State
n/a

Sponsors (1)

Lead Sponsor	Collaborator
Unity Health Toronto

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	To evaluate the impact of the HVIP on building personal capacity of youth who have experienced non-fatal violent injuries to thrive.	To evaluate changes in thriving, substance use, and mental health, validated measures and qualitative measures will be used. Quantitative measures collected using validated instruments will provide objective measures of change over time; while context-specific and nuanced growth will be captured through a semi-structured interview.	July 2024 - December 2025
Primary	To pilot the methodology proposed to measure the impact of THRIVE on subsequent injuries within 1 year using administrative data sources	After 1.5 years of enrolment in THRIVE, study participants will be deterministically linked. Linkage will provide a wealth of baseline characteristics (demographics, income/marginalization), injury characteristics (ICD-10 coding patterns which can be contrasted to THRIVE documentation), as well as the capacity to follow these linked patients administratively over time and identify subsequent ED presentations and admission across any hospital in Ontario.	March - Sept 2026