Vertebral Fracture Clinical Trial
Official title:
Identification of Cutaneous and Muscular Microcirculation and Inflammatory Response After Posterior Stabilization of the Spine
In this project, with unstable vertebral fractures, the microcirculation of the skin and muscle (O2C,Laser-Doppler/White-light -Spectroscopy and contrast-enhanced sonography) will be evaluated in both conventional and in percutaneous minimally invasive technique (XIA versus Mantis) at the thoracolumbar junction.
In this project, with unstable vertebral fractures, the microcirculation of the skin and
muscle (O2C,Laser-Doppler/Whitelight-Spectroscopy and contrast-enhanced sonography) will be
evaluated in both conventional and in percutaneous minimal-invasive technique (XIA versus
Mantis) at the thoracolumbar junction. And after placing a fixator, the inflammatory potency
(laboratory chemicals, cytokines, immune status) and the muscular injury (EMG) of acess are
examined.
The study is planned as a randomized prospective study. In the study a total of at least 100
patients should be included, 50 with minimally invasive fixation-implantation and 50
patients with conventional procedure.
The radiological imaging (post-surgical control, possibly after mobilization, CT) ist
routinely.
The patient outcome is determined using established scores (clinical score, visual analogue
scale, SF-12).
The study also indicates by comparing the damage of the microcirculation of the two surgical
techniques to make statements on wound healing and muscle blood flow heavily in order to
filter out the less complications and tissue-method.
In this research project, the limits in the microcirculation measurement with the O2C and
contrast enhanced sonography be established at an early stage to help in future wound
healing disorders can be treated so well.
;
Allocation: Randomized, Intervention Model: Single Group Assignment, Masking: Single Blind (Outcomes Assessor), Primary Purpose: Treatment
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Recruiting |
NCT06367582 -
SPINE BONE CEMENTS OUTCOMES
|
||
| Terminated |
NCT00748631 -
Treatment of Malignant Vertebral Fractures With Percutaneous Balloon Kyphoplasty.
|
N/A | |
| Completed |
NCT00463905 -
Evaluation of the Impact of a Case-finding Strategy for Vertebral Fractures
|
N/A | |
| Completed |
NCT03885466 -
Nordic Walking for Individuals With Osteoporosis, Vertebral Fracture or Hyperkyphosis
|
N/A | |
| Active, not recruiting |
NCT05283148 -
Sickle Cell Disease (SCD) Bone Pain Study
|
N/A | |
| Completed |
NCT03839732 -
Observer Variability in Scoring Abdominal Aortic Calcifications and Vertebral Morphometry
|
||
| Recruiting |
NCT04609150 -
Vertebral Fat Quantitative MRI as a Marker of Bone Fragility in Multiple Myeloma (MYELOMEFRAGIQUANTI)
|
||
| Completed |
NCT03263585 -
Treatment With a Spinal Orthosis Compared to Equipment Group Training and a Control Group
|
N/A | |
| Completed |
NCT02536898 -
Norwegian Capture the Fracture Initiative
|
N/A | |
| Completed |
NCT01963039 -
A Trial of Vertebroplasty for Painful Chronic Osteoporotic Vertebral Fractures (Vertos V)
|
N/A | |
| Completed |
NCT01120197 -
Study of Effect of Exercise With Osteoporosis and Vertebral Fracture
|
N/A | |
| Recruiting |
NCT04821739 -
RISE - Study of the AGN1 LOEP SV Kit in Patients With Vertebral Compression Fractures
|
N/A | |
| Completed |
NCT05071625 -
CT Guided Percutaneous Vertebroplasty for Vertebral Non-union Following Posterior Fixation
|
||
| Recruiting |
NCT04533217 -
Examination of Vertebroplasty in Addition to Regular Treatment of Patients With Multiple Myeloma.
|
N/A | |
| Completed |
NCT05227976 -
Patient Education With or Without Physical Training or Mindfulness and Medical Yoga in Established Spinal Osteoporosis
|
N/A | |
| Completed |
NCT04980131 -
Application of 3-Dimensional Printing Guide Template and Pointed Lotus-style Regulator
|
N/A | |
| Completed |
NCT01839682 -
Evaluation of Outcomes of DFine StabiliT Kyphoplasty in Vertebral Compression Fractures Due to Osteoporosis
|
N/A | |
| Not yet recruiting |
NCT06449742 -
A Prospective Observational Study of Artificial Intelligence Morphometric Evaluation of Vertebral Fractures
|
||
| Completed |
NCT03617094 -
Early Percutaneous Vertebroplasty Versus Standard Conservative Treatment in Thoracolumbar Vertebral Fractures
|
N/A | |
| Active, not recruiting |
NCT01374412 -
Investigation of Bone Defects and Microcirculation With Computed Tomography and Magnetic Resonance Imaging
|