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Venous Ethanol for Ventricular Tachycardia — VELVET  

Ventricular Tachycardia Clinical Trial

Official title:
Venous Ethanol for Ischemic Left Ventricular Tachycardia

Clinical Trial Summary

Comparative effectiveness randomized clinical trial, comparing endocardial radiofrequency ablation alone vs radiofrequency ablation combined with venous ethanol in patients with ischemic ventricular tachycardia -Venous Ethanol for Left Ventricular Ischemic Ventricular Tachycardia -VELVET clinical trial

Clinical Trial Description

Patients with ventricular tachycardia (VT) in the context of ischemic heart disease suffer from significant morbidity and mortality. Catheter ablation can improve outcomes but has suboptimal ablation results. Ethanol ablation via epicardial veins can add significant therapeutic value to catheter ablation by increasing reach to intramural VT substrates. Investigators will randomize patients with ischemic VT to either endocardial catheter ablation alone, or combined with venous ethanol (VE) ablation of coronary veins located on the epicardial aspect of the VT substrates. A combined primary endpoint: VT recurrence, procedural complications, hospitalization for cardiac causes, and death, will be measured over a 12-month follow-up. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05511246
Study type Interventional
Source The Methodist Hospital Research Institute
Contact Rene Plascencia
Phone 7134416548
Email rplascencia@houstonmethodist.org
Status Recruiting
Phase Phase 2
Start date April 12, 2023
Completion date December 12, 2028
View Details
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