"Ventricular Tachycardia Ablation Registry".

Status Active, not recruiting

Clinical Trial Summary

Catheter ablation of Ventricular Tachycardias is a well-established approach in clinical practice in patients with Implantable Cardioverter Defibrillator (ICD) implanted. Previous studies have shown a significant reduction in appropriate shocks (~ 20%) and a significant reduction in hospitalizations for cardiovascular reasons (~ 12%) in patients with ischemic heart disease treated with ablation. Recent works have also shown the effectiveness of the ablation procedure using as procedural target the reduction of late potentials. However, actually it is necessary to have an homogenize and accepted mapping scheme in Sinus Rhythm to ablate Ventricular Tachycardias related to scar substrate in patients with:

- Previous MI

- Previous myocarditis

- Arrhythmogenic Right Ventricular Dysplasia (ARVD)

- Idiopathic Dilated Cardiomyopathy (IDCM)

Scope of the registry is to collect data during cardiac mapping in Sinus Rhythm in patients indicated for Ventricular Tachycardia ablation, that will be performed per clinical practice, by using the St. Jude Medical EnSiteTM PrecisionTM mapping system.

The objective of the present registry is: to assess the acute and long-term efficacy of the strategy of substrate abolition (abolishment of complex and late potentials) guided by electroanatomic mapping with Precision software.

Clinical Trial Description

This is an Italian multicenter, observational, prospective and retrospective registry.

Data will be collected during enrollment/baseline, procedure, pre-discharge and during the follow-up visits according to the standard practice of participating centers, with mandatory visits at 6 and 12 months. Data can also be collected retrospectively, prior informed consent of the patient.

The planned enrollment duration is approximately 24 months. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT03649022
Study type	Observational [Patient Registry]
Source	IRCCS San Raffaele
Contact
Status	Active, not recruiting
Phase
Start date	July 25, 2017
Completion date	January 31, 2021

View Details

See also
Status	Clinical Trial	Phase
Recruiting	`NCT03453645` - Modification of Rhythmic Risk Assessment by Ventricular Tachycardia Ablation
Completed	`NCT05791032` - Sub Chronic Evaluation for ATP With an Extravascular Placed ICD Lead (STEP ICD) Study	N/A
Completed	`NCT05970120` - A Study of Intracardiac Ultrasound With the NUVISION NAV Ultrasound Catheter	N/A
Completed	`NCT04011631` - Evaluation of the iD-SystemTM, One-Handed Disposable Internal Defibrillation System.	N/A
Recruiting	`NCT03536052` - Ablation at Virtual-hEart pRedicted Targets for VT	N/A
Not yet recruiting	`NCT06063811` - Ventricular Tachycardia Ablation in LVAD Patients
Enrolling by invitation	`NCT02962076` - Study of Cardiac PET/CT Imaging to Guide Ablation Treatment of Ventricular Tachycardia	Early Phase 1
Not yet recruiting	`NCT02784912` - Biomarkers in Risk Stratification of Sustainted Ventricular Tachycardia or Electrical Storm After Ablation	N/A
Completed	`NCT01791543` - Intramural Needle Ablation for Ablation of Recurrent Ventricular Tachycardia	N/A
Terminated	`NCT02891863` - Low Energy Therapy to Convert Ventricular Tachycardias	Phase 0
Terminated	`NCT01546207` - Stepwise Approach To sUbstrate Modification for Ventricular Tachycardia	N/A
Completed	`NCT01294267` - Percutaneous Hemodynamic Support With Impella 2.5 During Scar-related Ventricular Tachycardia Ablation	N/A
Terminated	`NCT00383799` - Iv Amiodarone Versus Iv Procainamide to Treat Haemodynamically Well Tolerated Ventricular Tachycardia	Phase 4
Completed	`NCT04884100` - enHEART - Exploring Full Content of Optical Signals to Enhance Cardiac Arrhythmia Screening	N/A
Completed	`NCT04642963` - Stereotactic Management of Arrhythmia - Radiosurgery in Treatment of Ventricular Tachycardia	N/A
Recruiting	`NCT05377216` - Characterization of Cardiac Electrophysiological Effects of Autonomic Neuromodulation	Early Phase 1
Not yet recruiting	`NCT04990089` - VIVO European Observational Registry
Completed	`NCT04065893` - Impact of Catheter Ablation of Ventricular Arrhythmias on Suboptimal Biventricular Pacing in Cardiac Resynchronization Therapy
Recruiting	`NCT03631303` - Post-Extrasystolic Potentiation as a Predictor of Ventricular Arrhythmias
Recruiting	`NCT03611465` - Creation of a Pace-mapping Atlas on Healthy and Pathological Hearts	N/A