Ventricular Dysfunction, Left Clinical Trial
Official title:
Echocardiography-guided Hemodynamic (EGHEM) Management Strategy to Improve Clinical Outcomes for Elderly Patients With Left Ventricular Diastolic Dysfunction (LVDD) Undergoing Non-cardiac Surgery
Elderly patients are the fastest growing surgical population and have an increased risk of postoperative cardiac problems. Diastolic dysfunction, or the reduced ability of the heart' s ventricles to fill completely, is common in the elderly population and increases the risk of major adverse cardiac events after surgery. This study will measure diastolic filling and implement fluid and drug management during surgery to determine whether this reduces serious cardiac events related to diastolic dysfunction after surgery in this high-risk population.
Elderly patients are the fastest growing surgical population and present with increased risk of postoperative cardiac problems, especially congestive heart failure. Diastolic dysfunction is common in the elderly population and increases the risk of major adverse cardiac events after surgery. This project will use dynamic measurements of diastolic filling pressures by echocardiography for goal-directed fluid and drug management during surgery to determine whether this reduces serious cardiac events related to diastolic dysfunction after surgery in this high-risk population. ;
Status | Clinical Trial | Phase | |
---|---|---|---|
Completed |
NCT01959828 -
Confirmatory Study of IK-3001 in Japanese Subjects With Peri-/Post-op Pulmonary Hypertension Assoc. With Cardiac Surgery
|
Phase 3 | |
Recruiting |
NCT03385785 -
Ventriculo-arterial Coupling Modification Evaluated by PRAM During TAVI Procedure
|
N/A | |
Completed |
NCT02428894 -
Characterization of the Plasma Proteome Following Left Ventricular Assist Device Implantation
|
N/A | |
Completed |
NCT02147457 -
Prematurity as Predictor of Children's Cardiovascular-renal Health
|
N/A | |
Completed |
NCT00391846 -
Evaluation of Heart Failure Treatment Guided by N-terminal Pro B-type Natriuretic Peptide (NTproBNP) vs Clinical Symptoms and Signs Alone
|
Phase 4 | |
Enrolling by invitation |
NCT03701997 -
Registry to Monitor Berlin Heart EXCOR® Pediatric VAD as a Bridge to Cardiac Transplantation.
|
||
Not yet recruiting |
NCT05784051 -
Prophylactic Frequent Premature Ventricular complexeS sUPPression on Left ventriculaR Function impairmEnt in aSymptomatic patientS
|
Phase 4 | |
Recruiting |
NCT04939077 -
Treatment of Heart Failure Using Human Umbilical Cord Mesenchymal Stem Cells(hUC-MSC)
|
Phase 1/Phase 2 | |
Terminated |
NCT01065051 -
Hemodynamic and Echocardiographic Assessment of Riociguat Effects on Myocardial Wall Contractility and Relaxation Kinetics
|
Phase 2 | |
Terminated |
NCT00587990 -
Prospective Randomized Study of Mesenchymal Stem Cell Therapy in Patients Undergoing Cardiac Surgery (PROMETHEUS)
|
Phase 1/Phase 2 | |
Completed |
NCT02972918 -
Preoperative levosimendán and Hip Fracture
|
||
Completed |
NCT00303979 -
IMPROVE HF: Registry to Improve the Use of Evidence-Based Heart Failure Therapies in the Outpatient Setting
|
||
Withdrawn |
NCT02155842 -
Exercise Training in Treating Diastolic Heart Failure
|
N/A | |
Completed |
NCT00385242 -
PET and Recovery Following Revascularization (PARR 2)
|
Phase 3 | |
Terminated |
NCT01172756 -
A Study to Test the Effects of Riociguat in Patients With Pulmonary Hypertension Associated With Left Ventricular Diastolic Dysfunction
|
Phase 2 | |
Completed |
NCT02899897 -
Place of Echocardiography in IV Fluid Therapy in Patients With Septic Shock and Left Ventricular Systolic Dysfunction
|
||
Completed |
NCT02668419 -
Electrical Stimulation Improves Exercise Tolerance in Patients With Advanced Heart Failure on Continuous Dobutamine Use
|
N/A | |
Completed |
NCT01936649 -
Open-label, Test-retest Study Assessing Reproducibility of Quantitative Measurements of Myocardial Uptake of AdreView.
|
Phase 4 | |
Completed |
NCT01800292 -
Characterization of LV Strain Patterns in Mildly Elevated PCWP and PAH.
|
Phase 4 | |
Completed |
NCT00143507 -
The BEAUTIFUL Study: Effects of Ivabradine in Patients With Stable Coronary Artery Disease and Left Ventricular Systolic Dysfunction
|
Phase 3 |